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a-Amino ketones and 1,2-amino alcohols are important structural motifs in organic chemistry, that
can be observed in natural products, pharmaceutically and bioactive compounds. For these reasons,
they constitute privileged targets for the development of ne ...
The goal of this thesis was to find conditions to form C-C double bond and single bond using sulfonyl derivativies, which are arising from the Vogel's oxyallylation cascades. In a second chapter, it is shown that 2-methylprop-2-ene-1-sulfonyl fluorides can ...
A review with 64 refs., including discussion of the structural flexibility of organometallic species, the stereochem. of 2-alkenylmetal compds., and the origin of the endo effect. [on SciFinder (R)] ...
(2,6-Dichlorophenyl)- and (2,6-dibromophenyl)trialkylsilanes undergo hydrogen/metal interconversion preferentially at the 4- rather than 3-position. However, the organometallic species generated by such a "meta metalation" are thermodynamically less stab ...
Direct reaction between [Cr(CO)6] and arenes with ionic substituents affords the corresponding arene-chromium tricarbonyl complexes, [Cr(CO)3(arene)], in only modest yield. In contrast, these complexes can be prepared in pure form in ...
Methyl 2-deoxy-2-[(1S)-2.5-dideoxy-2.5-imino-L-ribitol-1-C-yl)-alpha-D-glucopyr anoside ((+)-6) was obtained from the product of Nozaki-Kishi coupling of 2,5-{[(tert-butoxy)carbonyl]imino}-2,5-dideoxy-3,4-O-isopropl-idene-L-ri bose ((-)-9) and 4-0-benzyl-6 ...
Transition-metal-catalyzed C-C coupling reactions have been extensively studied in the past three decades. These reactions have become invaluable to fundamental research and industrial applications, because they can be used construct complicated molecules ...
Sulphur dioxide reacts with 1-oxydienes generating zwitterions which are quenched by enoxysilanes to form substituted silyl alkenylsulfinates. These intermediates are desilylated with Bu4NF and the resulting sulfinates react with MeI giving the correspondi ...
C-C and C-N bonds are some of the most common structures in molecules ranging from drugs to catalysts and to food additives. Many coupling reactions were developed to form these types of bonds with excellent selectivity and good performance. Still, the syn ...
A copper-based method is highly efficient for the cross-coupling of alkyl electrophiles with secondary and tertiary alkyl Grignard reagents. The method is distinguished by its broad substrate scope and high functional group tolerance. ...
