Publications related to Carcinogenesis

Michaël Unser, Laurène Donati, Masih Nilchian

A central challenge in scanning transmission electron microscopy (STEM) is to reduce the electron radiation dosage required for accurate imaging of 3D biological nano-structures. Methods that permit tomographic reconstruction from a reduced number of STEM ...

2017

Metabolic Tumor Volume and Total Lesion Glycolysis in Oropharyngeal Cancer Treated With Definitive Radiotherapy: Which Threshold Is the Best Predictor of Local Control?

Adrien Raphaël Depeursinge

Purpose In the context of oropharyngeal cancer treated with definitive radiotherapy, the aim of this retrospective study was to identify the best threshold value to compute metabolic tumor volume (MTV) and/or total lesion glycolysis to predict local-region ...

Lippincott Williams & Wilkins2017

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Cathrin Brisken, Georgios Sflomos, Ayyakkannu Ayyanan, Laura Battista, Maryse Fiche, Valentina Scabia, Valérian Charles Robert Dormoy

Seventy-five percent of breast cancers are estrogen receptor α positive (ER(+)). Research on these tumors is hampered by lack of adequate in vivo models; cell line xenografts require non-physiological hormone supplements, and patient-derived xenografts (PD ...

Elsevier2016

Bioprinting the Cancer Microenvironment

Margaux Catherine Marie Duchamp

Cancer is intrinsically complex, comprising both heterogeneous cellular compositions and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell-cell interactions (involving vascular and immune cells besid ...

Amer Chemical Soc2016

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer

George Coukos, Nicolas Jean Philippe Guex, Luc Henry, Ioannis Xenarios, Hans-Anton Lehr, Nathalie Rufer, Emanuela Marina Iancu

In experimental mouse models of cancer, increasingly compelling evidence point toward a contribution of tumor associated macrophages (TAM) to tumor lymphangiogenesis. Corresponding experimental observations in human cancer remain scarce although lymphatic ...

Taylor & Francis Inc2016

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

Iacovos Michael

Intratumoral heterogeneity is an inherent feature of most human cancers and has profound implications for cancer therapy. As a result, there is an emergent need to explore previously unmapped mechanisms regulating distinct subpopulations of tumor cells and ...

National Academy of Sciences2016

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

Paloma Ordonez Moran

SPROUTY-2 (SPRY2) is a modulator of tyrosine kinase receptor signaling with receptor-and cell type-dependent inhibitory or enhancing effects. Studies on the action of SPRY2 in major cancers are conflicting and its role remains unclear. Here we have dissect ...

Nature Publishing Group2016

Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis

Oliver Hantschel, Sina Maren Reckel

The amount of genomic information about leukemia cells currently far exceeds our overall understanding of the precise genetic events that ultimately drive disease development and progression. Effective implementation of personalized medicine will require t ...

American Association for Cancer Research2016

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Carcinogenesis

Reprogramming tumor blood vessels for enhancing immunotherapy

Compressed sensing for STEM tomography

Metabolic Tumor Volume and Total Lesion Glycolysis in Oropharyngeal Cancer Treated With Definitive Radiotherapy: Which Threshold Is the Best Predictor of Local Control?

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Bioprinting the Cancer Microenvironment

Role of RIP4 in lung adenocarcinoma differentiation

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis

Graph Chatbot

Chat with Graph Search

Reprogramming tumor blood vessels for enhancing immunotherapy

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

Compressed sensing for STEM tomography

Metabolic Tumor Volume and Total Lesion Glycolysis in Oropharyngeal Cancer Treated With Definitive Radiotherapy: Which Threshold Is the Best Predictor of Local Control?

Bioprinting the Cancer Microenvironment

Role of RIP4 in lung adenocarcinoma differentiation

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis