Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Bernard MoretBernard M.E. Moret was born in Vevey, Switzerland, received baccalauréats in Latin-Greek and Latin-Mathematics, then did a Diploma in Electrical Engineering at EPFL. After working for 2 years for Omega and Swiss Timing on the development of real-time OS for sports applications, he left for the US. He received his PhD in Electrical Engineering from the U. of Tennessee in 1980 and joined the Department of Computer Science at the University of New Mexico (UNM) that fall. He served as Chairman of the department from 1991 till 1993 and eventually retired in summer 2006 to join the School of Computer and Communication Sciences at EPFL. (You can read about his work at UNM on his (archived) personal and laboratory web pages at UNM.) He was appointed group leader for phylogenetics at the Swiss Institute for Bioinformatics (SIB). From 2009 until his retirement, he was also in charge of the BS and MS programs in Computer Science and Associate Dean for Education. He founded the ACM Journal of Experimental Algorithmics (JEA) and served as its Editor-in-Chief for 7 years; he also helped found the IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), where he served as Associate Editor until 2008. He founded the annual Workshop on Algorithms in Bioinformatics (WABI) and chairs its steering committee, and he serves on the steering committee of the Workshop on Algorithm Engineering and Experiments (ALENEX). Until summer 2008, he chaired the Biodata Management and Analysis (BDMA) study section of the US National Institutes of Health (NIH); now he is a charter member of the NIH College of Reviewers. He led a team of over 50 biologists, computer scientists, and mathematicians in the CIPRES (Cyber Infrastructure for Phylogenetic Research) project, funded by the US National Science Foundation (NSF) for US$ 12 million over 5 years. He has published nearly 150 papers in computational biology, under funding from the US NSF, the Alfred P. Sloan foundation, the IBM Corporation, the US NIH, the Swiss NSF, and SystemsX.ch. He is a Fellow of the ISCB (International Society for Computational Biology). His Erdös number is 2 and (as of 2020) his h-index is 48.
Jacques FellayJacques Fellay is a medical scientist with expertise in infectious diseases and human genomics. He obtained his MD from the University of Lausanne in 2002 and his PhD from University of Utrecht. After a clinical training in infectious diseases in Switzerland and a 4-years postdoctoral fellowship at Duke University, he joined the EPFL in April 2011 with an SNF Professorship.
On top of his EPFL affiliation, Jacques is also Head of Precision Medicine at the University Hospital (CHUV) in Lausanne, Group Leader at the Swiss Institute of Bioinformatics, and Co-director of the Health2030 Genome Center at Campus Biotech in Geneva.
Jean-Pierre HubauxJean-Pierre Hubaux is a full professor at EPFL and head of the Laboratory for Data Security. Through his research, he contributes to laying the foundations and developing the tools for protecting privacy in today’s hyper-connected world. He has pioneered the areas of privacy and security in mobile/wireless networks and in personalized health. He is the academic director of the Center for Digital Trust (C4DT). He leads the Data Protection in Personalized Health (DPPH) project funded by the ETH Council and is a co-chair of the Data Security Work Stream of the Global Alliance for Genomics and Health (GA4GH). From 2008 to 2019 he was one of the seven commissioners of the Swiss FCC. He is a Fellow of both IEEE (2008) and ACM (2010). Recent awards: two of his papers obtained distinctions at the IEEE Symposium on Security and Privacy in 2015 and 2018. He is among the most cited researchers in privacy protection and in information security. Spoken languages: French, English, German, Italian
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Matteo Dal PeraroMatteo Dal Peraro graduated in Physics at the University of Padua in 2000. He obtained his Ph.D. in Biophysics at the International School for Advanced Studies (SISSA, Trieste) in 2004. He then received postdoctoral training at the University of Pennsylvania (Philadelphia) under the guidance of Prof. M. L. Klein. He was nominated Tenure Track Assistant Professor at the EPFL School of Life Sciences in late 2007.
His research at the Laboratory for Biomolecular Modeling (LBM), within the Interfaculty Institute of Bioengineering (IBI), focuses on the multiscale modeling of large macromolecular systems.