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Concept
Sertoli cell nodule
Summary
A Sertoli cell nodule is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an adenoma.
TOC
Sertoli cell nodules are unencapsulated nodules that consist of:
cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with
bland hyperchromatic oval/round nuclei that are stratified, and
may contain eosinophilic (hyaline) blob in lumen (centre).
Image:Sertoli cell nodule intermed mag.jpg|[[Micrograph]] of a Sertoli cell nodule. [[H&E stain]].
Image:Sertoli cell nodule low mag.jpg|[[Micrograph]] of a Sertoli cell nodule. [[H&E stain]].
Official source
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