Concept

Sertoli cell nodule

Summary
A Sertoli cell nodule is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an adenoma. TOC Pathology Sertoli cell nodules are unencapsulated nodules that consist of:

cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with

bland hyperchromatic oval/round nuclei that are stratified, and

may contain eosinophilic (hyaline) blob in lumen (centre).

Image:Sertoli cell nodule intermed mag.jpg|[[Micrograph]] of a Sertoli cell nodule. [[H&E stain]]. Image:Sertoli cell nodule low mag.jpg|[[Micrograph]] of a Sertoli cell nodule. [[H&E stain]].
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