Concept

Stephen J. O'Brien

Summary
Stephen J. O'Brien (born 1944) is an American geneticist. He is known for his research contributions in comparative genomics, virology, genetic epidemiology, mammalian systematics and species conservation. Member of the National Academy of Sciences and a Foreign Member of the Russian Academy of Sciences. Author or co-author of over 850 scientific articles and the editor of fourteen volumes. From 1986 to 2011, O'Brien served as Chief of the Laboratory of Genomic Diversity at the National Cancer Institute (NCI), National Institutes of Health (NIH). In December 2011, he created the Theodosius Dobzhansky Center for Genome Bioinformatics (named after Theodosius Dobzhansky) at St. Petersburg State University, Russia as Chief Scientific Officer. In January 2013, he joined the Faculty as Professor at the Oceanographic Center, Nova Southeastern University, Ft Lauderdale Florida. Since November 2019, O'Brien serves as Professor at the Center of Genomic Diversity at ITMO University, St. Petersburg, Russia. O’Brien received his B.S. in Biology in 1966 from St. Francis College, which presented him with a Distinguished Alumni Award in 1994. In 1971 he earned a Ph.D. in Genetics from Cornell University which honored him as “Andrew Dixon White Endowed Professor at Large” in 1998. At Cornell, he expanded the nascent discipline of biochemical genetics, developing the gene-enzyme maps of Drosophila melanogaster. His biochemical mapping would stimulate his editing of six editions of Genetic Maps: Locus Maps of Complex Genomes (1980-1993) (Cold Spring Harbor Laboratory Publications), international unabridged compendiums of plant, animal, bacteria and virus genetic maps that were prelude to the online NCBI gene mapping databases of species whole genome DNA sequences. In 1983, he and his collaborators discovered the close genetic uniformity of the African cheetah, a prelude to a new discipline of Conservation Genetics.
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