Publications related to Behavioural genetics

Efficient inference for genetic association studies with multiple outcomes

Anthony Christopher Davison, Jörg Hager, Hélène Ruffieux

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single clinical outcome on ma ...

Oxford University Press2017

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Jean-Pierre Hubaux, Jacques Fellay, Zhicong Huang, Huang Lin

Motivation: Due to the limited power of small-scale genome-wide association studies (GWAS), researchers tend to collaborate and establish a larger consortium in order to perform large-scale GWAS. Genome-wide association meta-analysis (GWAMA) is a statistic ...

Oxford University Press2017

Variant selection in surface martensite

Roland Logé, Cyril Cayron, Annick Pauline Baur

A significant variant selection is reported in isothermal martensite formed on the surface of an Fe-30% Ni sample. The selection phenomenon is modelled using different descriptions of the martensitic phase transformation. In particular, matrices based on t ...

International Union of Crystallography2017

{225} habit planes in martensitic steels: from the PTMC to a continuous model

Roland Logé, Cyril Cayron, Annick Pauline Baur

Fine twinned microstructures with {225}γ habit planes are commonly observed in martensitic steels. The present study shows that an equibalanced combination of twin-related variants associated to the Kurdjumov-Sachs orientation relationship is equivalent to ...

Nature Publishing Group2017

Open computational landscape genetics

Stéphane Joost, Estelle Rochat, Ivo Widmer

Geographical Information Systems (GIS) are considered to be applications-led technology. Consequently, geographic information scientists commonly find themselves as guest in host disciplines in order to best exploit spatial analysis tools and methods, appr ...

2016

Joint mouse-human phenome-wide association to test gene function and disease risk

Johan Auwerx, Zhi Li, Evan Graehl Williams, Xu Wang, Virginija Jovaisaite

Phenome-wide association is a novel reverse genetic strategy to analyze genome-to-phenome relations in human clinical cohorts. Here we test this approach using a large murine population segregating for similar to 5 million sequence variants, and we compare ...

Nature Publishing Group2016

The genetics of social hierarchies

Maria del Carmen Sandi Perez, Michael van der Kooij

The organization of individuals in social hierarchies is ubiquitous in social species. Although the evolution of dominance at the population level is constrained by its interactive character, selective breeding shows that dominance and subordination can be ...

2015

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Jacques Fellay, Amalio Telenti, Istvan Bartha

Previous genome-wide association studies (GWAS) of HIV-1-infected populations have been underpowered to detect common variants with moderate impact on disease outcome and have not assessed the phenotypic variance explained by genome-wide additive effects. ...

Natl Acad Sciences2015

Experimental testing and finite element modelling of earth block masonry

Angelo Garofano, Urs Müller

The current paper focuses on the determination of reliable numerical models of earth block masonry wallettes under different loading conditions. Uniaxial compression and diagonal compression tests were performed. Experimental behaviour was modelled with a ...

Elsevier2015

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Behavioural genetics

Efficient inference for genetic association studies with multiple outcomes

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Variant selection in surface martensite

{225} habit planes in martensitic steels: from the PTMC to a continuous model

Open computational landscape genetics

Joint mouse-human phenome-wide association to test gene function and disease risk

Cognitive markers as potential endophenotypes for schizophrenia

The genetics of social hierarchies

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Experimental testing and finite element modelling of earth block masonry

Graph Chatbot

Chat with Graph Search

{225} habit planes in martensitic steels: from the PTMC to a continuous model

Cognitive markers as potential endophenotypes for schizophrenia

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Variant selection in surface martensite

Open computational landscape genetics

Efficient inference for genetic association studies with multiple outcomes

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Joint mouse-human phenome-wide association to test gene function and disease risk

Experimental testing and finite element modelling of earth block masonry

The genetics of social hierarchies