Concept

Electrophysiology study

Related publications (37)

MATHICSE Technical Report : Numerical approximation of parametrized problems in cardiac electrophysiology by a local reduced basis method

Alfio Quarteroni, Andrea Manzoni, Stefano Pagani

The efficient solution of coupled PDEs/ODEs problems arising in cardiac electrophysiology is of key importance whenever interested to study the electrical behavior of the tissue for several instances of relevant physical and/or geometrical parameters. This ...

MATHICSE2017

A reconstruction algorithm based on topological gradient for an inverse problem related to a semilinear elliptic boundary value problem

Andrea Manzoni

In this paper we develop a reconstruction algorithm for the solution of an inverse boundary value problem dealing with a semilinear elliptic partial differential equation of interest in cardiac electrophysiology. The goal is the detection of small inhomoge ...

Institute of Physics2017

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a compl ...

Elsevier Science Sa2017

An asymptotic formula for boundary potential perturbations in a semilinear elliptic equation related to cardiac electrophysiology

Andrea Manzoni

In this paper, we provide a representation formula for boundary voltage perturbations caused by internal conductivity inhomogeneities of low volume fraction in a simplified monodomain model describing the electrical activity of the heart. We derive such a ...

World Scientific Publishing2016

MATHICSE Technical Report : Integrated Heart – Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modelling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a comp ...

MATHICSE2016

Mathematical modeling and numerical simulation of excitation-contraction phenomena in the heart

In this Master thesis we aim at studying some physiological and computational aspects of the excitation-contraction mechanisms in the heart muscle. This phenomenon exhibits many complexities at different spatio-temporal scales. The relevance and applicabil ...

2013

PDMS Microchannel Regenerative Peripheral Nerve Interface

Stéphanie Lacour, Katherine Marie Musick

We have fabricated a soft silicone structure to support the regeneration of a sciatic nerve. The device consists of 70 parallel (120 x 110 mu m(2)) channels through which axons extend and then reconnect to the muscles on the other side of the device. Throu ...

Ieee2013

Analysis of an optimal control problem for the tridomain model in cardiac electrophysiology

Ricardo Esteban Ruiz Baier

In the present paper, an optimal control problem constrained by the tridomain equations in electrocardiology is investigated. The state equations consisting in a coupled reaction-diffusion system modelling the propagation of the intracellular and extracell ...

Elsevier2012

Microfabricated Multimode Bio-interface with High Density Microelectrode Array and Photonic Detectors

Mohssen Moridi

Presently, the cells' electrical activity is measured either by extracellular microelectrode array (MEA) or by microscopic fluorescence imaging methods. The MEA is a non-invasive in vitro technique which allows long-term recording at multicellular level wh ...

EPFL2011

Therapeutic Strategies for the Treatment of Atrial Fibrillation

Laurent Renaud Uldry

Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...

EPFL2011

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