Set cover problemThe set cover problem is a classical question in combinatorics, computer science, operations research, and complexity theory. It is one of Karp's 21 NP-complete problems shown to be NP-complete in 1972. Given a set of elements {1, 2, ..., n} (called the universe) and a collection S of m sets whose union equals the universe, the set cover problem is to identify the smallest sub-collection of S whose union equals the universe. For example, consider the universe U = {1, 2, 3, 4, 5} and the collection of sets S = { {1, 2, 3}, {2, 4}, {3, 4}, {4, 5} }.