Concept

Phospholipid

Related publications (82)

fumble encodes a pantothenate kinase homolog required for proper mitosis and meiosis in Drosophila melanogaster

A number of fundamental processes comprise the cell division cycle, including spindle formation, chromosome segregation, and cytokinesis. Our current understanding of these processes has benefited from the isolation and analysis of mutants, with the meioti ...

2001

Surface dynamics of aerolysin on the plasma membrane of living cells

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

Aerolysin secreted by the human pathogen Aeromonas hydrophila belongs to a group of bacterial toxins that are hemolytic and form channels in biological membranes. The toxin is secreted as an inactive precursor proaerolysin that must be proteolytically proc ...

2000

The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition

Stewart Cole

The lethal, cytolytic alpha-toxin (phospholipase C) of Clostridium perfringens consists of two distinct modules: the larger N-terminal domain catalyses phospholipid hydrolysis, and its activity is potentiated by a smaller C-terminal domain. Calcium ions ar ...

1998

Determination of the surface concentration of crown ethers in supported lipid membranes by capacitance measurements

Michael Graetzel, Horst Vogel, Samuel Terrettaz

The attachment of a tetradecyl chain to the ionophore 18-crown-6 leads to a stronger interaction with a supported lipid monolayer. Some C14-18-crown-6 mols. introduced in the aq. phase are incorporated in the phospholipid membrane. This process is used to ...

1998

Photoemission analysis of chemical differences between the membrane and cytoplasm of neuronal cells

Giorgio Margaritondo

We demonstrate the possibility of using x-ray photoemission spectroscopy (XPS) to distinguish between the chemical properties of the neuron membrane and of the cytoplasm in brain cells. This was possible by analysing cells de-capped by using a newly develo ...

1997

Antibody Binding to a Functionalized Supported Lipid Layer: A Direct Acoustic Immunosensor

Horst Vogel, Martha Liley

A direct immunosensor has been developed using an acoustic wave device as a transducer. The device is based on an acoustic waveguide geometry that supports a Love wave. The biorecognition surface, formed on a gold layer, consisted of a biotinylated support ...

1997

Incorporation and antibody recognition of a lipid-anchored membrane protein in supported lipid layers

Horst Vogel, Martha Liley

The formation of supported lipid layers incorporating promastigote surface protease (PSP), a glycosylphosphatidylinositol-anchored protein, is investigated using surface plasmon resonance. Both hydrophilic and hydrophobic substrates are used for the format ...

1997

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) potentiate the glutamate-evoked release of arachidonic acid from mouse cortical neurons: Evidence for a cAMP-independent mechanism

Pierre Magistretti

Glutamatergic neurotransmission is associated with release of arachidonic acid (AA) from membrane phospholipids of both neurons and astrocytes. Since free AA has been shown to enhance glutamate-mediated synaptic transmission, it can be postulated that glut ...

1996

Sulfur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterization and analysis

Shaik Mohammed Zakeeruddin, Horst Vogel, Henning Paul-Julius Stahlberg, Jacques Dubochet, Martha Liley, Claus Duschl

In a recent paper, a new class of synthetic lipids, which self-assemble to form monolayers on gold surfaces, was introduced. The addn. of a monolayer of phospholipids to these layers results in robust supported lipid bilayers designed to reconstitute trans ...

1996

Covalent attachment of functionalized lipid bilayers to planar waveguides for measuring protein binding to biomimetic membranes

Horst Vogel

A new method is presented for measuring sensitively the interactions between ligands and their membrane-bound receptors in situ by using integrated optics, thus avoiding the need for addnl. labels. Phospholipid bilayers were attached covalently to waveguid ...

1995

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