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Background Migraine is a neurovascular disorder in which altered functional connectivity between pain-modulating circuits and the limbic system may play a role. Cortical spreading depression (CSD), which underlies migraine aura (MWA), induces C-fos express ...
A ergonomic handle that can be added to existing haptic devices, composed by a spherical mechanism providing hand orientation and a grasping mechanism is shown. Both the proposed spherical mechanism and the handle have been ergonomically designed to avoid ...
Background Loss of urinary control after spinal cord injury increases risk of urinary tract disease and is problematical for owners of affected dogs. Objectives To design, implant, and test a sacral nerve stimulating device for controlling urine voiding in ...
Introduction: Magnetic resonance imaging (MRI) is an excellent imaging modality for soft tissues. Magnetization transfer (MT) imaging is an MRI technique that is sensitive to the bound protons of macromolecules and therefore can aid in the assessment of ne ...
Peripheral neuropathic pain is a disabling condition resulting from nerve injury. It is characterized by the dysregulation of voltage-gated sodium channels (Na(v)s) expressed in dorsal root ganglion (DRG) sensory neurons. The mechanisms underlying the alte ...
A 16-channel neural action potential recording IC suitable for large-scale integration with multi-electrode arrays (MEAs) is presented. A closed-loop gain of 60 dB in the action potential band is achieved by cascading differential gain-stages utilizing a n ...
The ability of tracking peripheral nerves in foot could be of great benefit for a number of investigations, which include traumas, diabetes and infections. Previous approaches to nerve tracking have employed diffusion tensor imaging (DTI, [1, 2]), which is ...
Purpose: To measure the proton density (PD), the T1 and T2 relaxation time, and magnetization transfer (MT) effects in human median nerve at 3 T and to compare them with the corresponding values in muscle. ...
Array electrodes are a promising technology that is likely to bring transcutaneous electrical stimulation (TES) a step forward. The dynamic adaptation of electrode size and position helps to simplify the use of electrical stimulation systems and to increas ...
This article examines the T2 relaxation characteristics of the median nerve. Knowledge of the T2 relaxation time is essential to optimize clinical magnetic resonance imaging (MRI) protocols and to enhance the visibility of pathophysiological changes in tis ...