Concept

Genetic counseling

Related publications (221)

Adaptations to Climate-Mediated Selective Pressures in Sheep

Following domestication, sheep (Ovis aries) have become essential farmed animals across the world through adaptation to a diverse range of environments and varied production systems. Climate-mediated selective pressure has shaped phenotypic variation and h ...

Oxford Univ Press2014

Data integration, GIS and multi-criteria decision making for the monitoring of livestock genomic resources

Stéphane Joost

In 2007, FAO initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR) to reduce further loss of genetic diversity in farm animals. One of the key issues mentioned is to identify endangered breeds to support conservation prioritization ...

2014

Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus

Keratoconus, a common inherited ocular disorder resulting in progressive corneal thinning, is the leading indication for corneal transplantation in the developed world. Genome-wide association studies have identified common SNPs 100 kb upstream of ZNF469 s ...

Oxford University Press2014

Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons

Jacques Fellay, Amalio Telenti, Xuan Li

Background. Persons infected with human immunodeficiency virus (HIV) have increased rates of coronary artery disease (CAD). The relative contribution of genetic background, HIV-related factors, antiretroviral medications, and traditional risk factors to CA ...

Oxford University Press2013

Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine

Jean-Pierre Hubaux, Jacques Rougemont, Erman Ayday, Jean Louis Raisaro

In this paper, we propose privacy-enhancing technologies for medical tests and personalized medicine methods that use patients' genomic data. Focusing on genetic disease-susceptibility tests, we develop a new architecture (between the patient and the medic ...

2013

Privacy-Preserving Processing of Raw Genomic Data

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro, Adam Molyneaux, Urs Beda Hengartner

Geneticists prefer to store patients' aligned, raw genomic data, in addition to their variant calls (compact and summarized form of the raw data), mainly because of the immaturity of bioinformatic algorithms and sequencing platforms. Thus, we propose a pri ...

2013

Privacy-Preserving Processing of Raw Genomic Data

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro, Adam Molyneaux, Urs Beda Hengartner

Geneticists prefer to store patients’ aligned, raw genomic data, in addition to their variant calls (compact and summarized form of the raw data), mainly because of the immaturity of bioinformatic algorithms and sequencing platforms. Thus, we propose a pri ...

2013

An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker

Rolf Gruetter, Patrick Aebischer, Bernard Schneider, Philippe Guillaume Coune, Mélanie Craveiro, Meret Gaugler

The detection of Parkinson's disease (PD) in its preclinical stages prior to outright neurodegeneration is essential to the development of neuroprotective therapies and could reduce the number of misdiagnosed patients. However, early diagnosis is currently ...

Wiley-Blackwell2013

Integrating landscape genomics and spatially explicit approaches to detect loci under selection in clinal populations

Stéphane Joost

Uncovering the genetic basis of adaptation hinges on the ability to detect loci under selection. However, population genomics outlier approaches to detect selected loci may be inappropriate for clinal populations or those with unclear population structure ...

Wiley-Blackwell2013

Comment une situation d’investigation policière fait évoluer les conceptions d’élèves de troisième sur l’ADN

The work presented focuses on the analysis of a police investigation implemented in the computing environment SCY-Lab. The prime objective is to check if the implementation of the situation helps pupils change their conceptions concerning the DNA molecule ...

2013

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