Concept

Quantitative revolution

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Water use and quality in life cycle assessment

Anna Kounina Massé

Pressure on freshwater resources is increasingly covered by methodological developments addressing freshwater use in the field of Life Cycle Assessment (LCA). These developments ultimately lead to the publication of the ISO 14046 standard to define the pri ...

EPFL2014

Theoretical Framework for the Assessment of Uncertainties in Snow Depth Measurements

Michael Lehning, Ernesto Trujillo Gomez

In recent years, marked improvements in our knowledge of the statistical properties of the spatial distribution of snow properties have been achieved thanks to improvements in measuring technologies (e.g., LIDAR, TLS, and GPR). Despite of this, objective a ...

2014

Cortical Columns, Models of

Sean Lewis Hill

The annual Computational Neuroscience Meeting (CNS) began in 1990 as a small workshop called Analysis and Modeling of Neural Systems. The goal of the workshop was to explore the boundary between neuroscience and computation. Riding on the success of severa ...

Springer2014

Nonlinear Mode-Coupling in Nanomechanical Systems

Luis Guillermo Villanueva Torrijo

Understanding and controlling nonlinear coupling between vibrational modes is critical for the development of advanced nanomechanical devices; it has important implications for applications ranging from quantitative sensing to fundamental research. However ...

2013

Massively parallel measurements of molecular interaction kinetics on a microfluidic platform

Sebastian Maerkl, Marcel Geertz

Quantitative biology requires quantitative data. No high-throughput technologies exist capable of obtaining several hundred independent kinetic binding measurements in a single experiment. We present an integrated microfluidic device (k-MITOMI) for the sim ...

Natl Acad Sciences2012

Slum Upgrading in developing countries

Jean-Claude Bolay

The slum question is at the very heart to urban planning and social development. The urban growth takes place primarily in developing countries. Around one billion of people (with a perspective of 2 billion in 2030), the third of the world’s total urban po ...

2011

Slum Upgrading Interdisciplinary Perspective and Intersectoral Action

Jean-Claude Bolay

The slum question is not marginal to urban planning and social development – it is at its very heart. All the more so now that urban growth takes place primarily in developing countries in which populations move from rural to urban regions at a very fast p ...

2011

Stochastic Generation of Wind Patterns over Lake Geneva

David Andrew Barry, Ulrich Lemmin, Amir Mehdi Razmi, Nicolas Le Dantec, Caitlin Ellen Barry

Lake Geneva (length 74 km on the long east-west axis, surface area 562 km2, volume 89 km3) is a freshwater lake bordered by Switzerland and France. The lake’s hydrodynamics are forced principally by wind and seasonality, with inflows and the Coriolis effec ...

2011

Single-Particle Tracking Photoactivated Localization Microscopy For Mapping Single-Molecule Dynamics

Suliana Manley

Recent developments in single-molecule localization techniques using photoactivatable fluorescent proteins have allowed the probing of single-molecule motion in a living cell with high specificity, millisecond time resolution, and nanometer spatial resolut ...

2010

Quantitative approaches in developmental biology

Andrew Charles Oates

The tissues of a developing embryo are simultaneously patterned, moved and differentiated according to an exchange of information between their constituent cells. We argue that these complex self-organizing phenomena can only be fully understood with quant ...

2009