Concept
Marker gene
Related publications (28)
A self-immunomodulating myoblast cell line for erythropoietin delivery
Patrick Aebischer, Bernard Schneider
The transplantation of genetically engineered cells faces limitations associated with host immunity. Allogeneic cells are typically rejected in response to inherent histo-incompatibility. Even autologous cells can induce an immune response toward antigenic ...
2001Too much interference: Injection of double-stranded RNA has nonspecific effects in the zebrafish embryo
We have investigated the ability of double-stranded RNA (dsRNA) to inhibit gene expression in a vertebrate, the zebrafish, Danio rerio. Injection of dsRNA corresponding to the T-box gene tbx16/spadetail (spt) into early wild-type embryos caused a rapid and ...
2000Synthesis of alpha-C(1 -> 3)-mannopyranoside of N-acetylgalactosamine, a new beta-galactosidase inhibitor
Radical C-glycosidation of a 3-methylidene-7-oxabicyclo[2.2.1]heptan-2-one derivative with acetobromomannose gave a alpha-C-mannopyranoside that was converted into alpha-D-ManpCH(2)(1-->3)-D-GalNAc, a C-disaccharide that inhibits beta-galactosidase from ja ...
1999Drosophila immunity: analysis of larval hemocytes by P-element-mediated enhancer trap
Our aim was to identify new genes involved in the cellular aspects of defense mechanism of Drosophila, as well as in melanotic tumor formation processes that are linked to blood cell disregulation. We have screened 1341 enhancer detector fly lines for expr ...
Genetics Society of America1997Tyrosinase, the key enzyme in melanin synthesis, is expressed in murine brain
Tyrosinase is one of the key enzymes in mammalian melanin synthesis. The pigment is produced in two different cell types: the pigmented epithelial cell of the retina, and the melanocyte, a cell of neural-crest origin. We recently showed that a fusion gene ...
1996