Publications related to Developmental plasticity

A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Kathryn Hess Bellwald, Lida Kanari, Martina Scolamiero

Environmental cues influence the highly dynamic morphology of microglia. Strategies to characterize these changes usually involve user-selected morphometric features, which preclude the identification of a spectrum of context-dependent morphological phenot ...

NATURE PORTFOLIO2022

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

Grégoire Courtine, Quentin Barraud, Claudia Kathe, Thomas Haynes Hutson, Kay Alexander Bartholdi

After a spinal cord injury, axons fail to regenerate in the adult mammalian central nervous system, leading to permanent deficits in sensory and motor functions. Increasing neuronal activity after an injury using electrical stimulation or rehabilitation ca ...

AMER ASSOC ADVANCEMENT SCIENCE2019

Plastic and genetic responses of a common sedge to warming have contrasting effects on carbon cycle processes

Luca Bragazza, Constant Signarbieux, Richard David Bardgett, Thomas William Nicholas Walker

Climate warming affects plant physiology through genetic adaptation and phenotypic plasticity, but little is known about how these mechanisms influence ecosystem processes. We used three elevation gradients and a reciprocal transplant experiment to show th ...

2019

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Dimitri Nestor Alice Van De Ville, Maude Schneider, Marie Schaer, Jonas Richiardi, Fikret Isik Karahanoglu

The 22q11.2 deletion syndrome (22q11DS) is associated with cognitive impairments and a 41% risk of developing schizophrenia. While several studies performed on patients with 22q11DS showed the presence of abnormal functional connectivity in this syndrome, ...

Elsevier Masson2016

Structural to functional synaptic conversion

Henry Markram, Felix Schürmann, Sean Lewis Hill, Eilif Benjamin Muller, Michael Reimann, James Gonzalo King

Computer-implemented methods, software, and systems for determining functional synapses from given structural touches between cells in a neuronal circuit are described. One computer-implemented method for determining functional synapses from predetermined ...

Technology Transfer Office EPFL2015

Epigenetic Alterations in Alzheimer's Disease

Johannes Gräff, Jose Vicente Sanchez Mut

Alzheimer's disease (AD) is the major cause of dementia in Western societies. It progresses asymptomatically during decades before being belatedly diagnosed when therapeutic strategies have become unviable. Although several genetic alterations have been as ...

Frontiers Research Foundation2015

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Developmental plasticity

A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

Plastic and genetic responses of a common sedge to warming have contrasting effects on carbon cycle processes

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Structural to functional synaptic conversion

Epigenetic Alterations in Alzheimer's Disease

Nuclear protein phosphatase-1: an epigenetic regulator of fear memory and amygdala long-term potentiation

Epigenetics of brain disorders

Graph Chatbot

Chat with Graph Search

Epigenetic Alterations in Alzheimer's Disease

Plastic and genetic responses of a common sedge to warming have contrasting effects on carbon cycle processes

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Structural to functional synaptic conversion

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Nuclear protein phosphatase-1: an epigenetic regulator of fear memory and amygdala long-term potentiation

Epigenetics of brain disorders