Concept
Calcium channel blocker
Related publications (44)
Identification and Functional Response of "Interstitial Cells of Cajal"-like Cells from Rat Mesenteric Artery
Aurélie Formey de Saint Louvent
This thesis is a contribution to the field of interstitial cells of Cajal-like cells (ICC-LCs) in the vasculature. Indeed, cells with irregular shapes and numerous long thin filaments, morphologically similar to the gastrointestinal ICCs, have been observe ...
EPFL2011Therapeutic Strategies for the Treatment of Atrial Fibrillation
Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...
EPFL2011The electro-deoxidation of dense titanium dioxide precursors in molten calcium chloride giving a new reaction pathway
Duncan Thomas Lindsay Alexander
A new study is presented on the electro-deoxidation of porous TiO2 precursors in molten calcium chlo- ride electrolytes. It is shown that by reducing precursor open porosity from standard values of ≥25% to ∼11–12%, such that there is insufficient free volu ...
Elsevier2011Mechanisms of Propagation of Intercellular Calcium Waves in Arterial Smooth Muscle Cells
Jean-Jacques Meister, Jean-Louis Bény, Michèle Koenigsberger, Dominique Seppey
In rat mesenteric arteries, smooth muscle cells exhibit intercellular calcium waves in response to local phenylephrine stimulation. These waves have a velocity of similar to 20 cells/s and a range of similar to 80 cells. We analyze these waves in a theoret ...
Elsevier2010Ozonation of reverse osmosis concentrate: Kinetics and efficiency of beta blocker oxidation
Reverse osmosis (RO) concentrate samples were obtained from a RO-membrane system that uses effluents of wastewater treatment plants (WWTP) as feed water for the production of drinking water. A number of different pharmaceuticals (e.g. antibiotics, contrast ...
2008Calcium dynamics and vasomotion in arteries subject to isometric, isobaric, and isotonic conditions
Jean-Jacques Meister, Roger Sauser, Jean-Louis Bény, Michèle Koenigsberger, Dominique Seppey
In vitro, different techniques are used to study the smooth muscle cells' calcium dynamics and contraction/relaxation mechanisms on arteries. Most experimental studies use either an isometric or an isobaric setup. However, in vivo, a blood vessel is neithe ...
2008Mathematical models of cerebral hemodynamics for detection of vasospasm in major cerebral arteries
Cerebral vasospasm is a typical complication occurring after Subarachnoid Hemorrhage, which may
lead to delayed cerebral ischemia and death. The standard method to detect vasospasm is
angiography, which is an invasive procedure. Monitoring of vasospasm i ...
2008A theoretical model of the cellular calcium dynamics and vasomotion in muscular arteries
Muscular arteries possess the ability to control actively their lumen by altering the tone of the smooth muscle cells of the arterial wall, a property which is vital for a large number of the hemodynamical functions of the body. Arterial contraction is due ...
EPFL2006Effects of arterial wall stress on vasomotion
Jean-Jacques Meister, Roger Sauser, Jean-Louis Bény, Michèle Koenigsberger
Smooth muscle and endothelial cells in the arterial wall are exposed to mechanical stress. Indeed blood flow induces intraluminal pressure variations and shear stress. An increase in pressure may induce a vessel contraction, a phenomenon known as the myoge ...
Elsevier2006The effect of a myocardial infarction on the normalized time-varying elastance curve
Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, David Jegger
It has been suggested that the shape of the normalized time-varying elastance curve [E(n)(t(n))] is conserved in different cardiac pathologies. We hypothesize, however, that the E(n)(t(n)) differs quantitatively after myocardial infarction (MI). Sprague-Da ...
2006