Concept

Hippocampal sclerosis

Related publications (43)

Depersonalization- and derealization-like phenomena of epileptic origin

Olaf Blanke, Lukas Heydrich, Nathaniel Evans

Objective Depersonalization refers to the sensation of being detached from one's body, often associated with feelings of loss of control over one's own body, actions, or thoughts. Derealization refers to the altered perception of one's surroundings that is ...

2019

A challenge of predicting seizure frequency in temporal lobe epilepsy using neuroanatomical features

Chang-Hyun Park

The pathological and clinical characteristics of temporal lobe epilepsy (TLE) tend to be affected by epileptic seizures, specifically represented by seizure lateralization and frequency. Although the lateralization of the epileptogenic zone can be clarifie ...

ELSEVIER IRELAND LTD2019

Temporal Dissociation of Neocortical and Hippocampal Contributions to Mental Time Travel Using Intracranial Recordings in Humans

Olaf Blanke

In mental time travel (MTT) one is "traveling" back-and-forth in time, remembering, and imagining events. Despite intensive research regarding memory processes in the hippocampus, it was only recently shown that the hippocampus plays an essential role in e ...

2018

Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans

Silvestro Micera, Stanisa Raspopovic, Fiorenzo Artoni, Francesco Maria Petrini, Fabrizio Vecchio

Restoration of touch after hand amputation is a desirable feature of ideal prostheses. Here, we show that texture discrimination can be artificially provided in human subjects by implementing a neuromorphic real-time mechano-neuro-transduction (MNT), which ...

Elife Sciences Publications Ltd2016

Lateralising value of experiential hallucinations in temporal lobe epilepsy

Olaf Blanke, Lukas Heydrich, Nathaniel Evans

Objectives Ever since John Hughlings Jackson first described the so-called 'dreamy state' during temporal lobe epilepsy, that is, the sense of an abnormal familiarity (deja vu) or vivid memory-like hallucinations from the past (experiential hallucinations) ...

Bmj Publishing Group2015

The mechanisms of spatial and temporal patterning of cell-edge dynamics

Adherent cells migrate and change their shape by means of protrusion and retraction at their edges. When and where these activities occur defines the shape of the cell and the way it moves. Despite a great deal of knowledge about the structural organizatio ...

Elsevier2015

Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS

Interest in RNA dysfunction in amyotrophic lateral sclerosis (ALS) recently aroused upon discovering causative mutations in RNA-binding protein genes. Here, we show that extensive down-regulation of miRNA levels is a common molecular denominator for multip ...

Wiley-Blackwell2015

Structural Graph Analysis of Left and Right Temporal Lobe Epilepsy using Diffusion Spectrum Imaging

Jean-Philippe Thiran, Alessandro Daducci, Alia Lemkaddem, François Lazeyras

Patients with Temporal Lobe Epilepsy (TLE) suffer from widespread subtle white matter abnormalities and abnormal functional connectivity extending beyond the affected lobe, as revealed by volumetric and functional MRI studies. Diffusion Magnetic Resonance ...

2014

Impairment of semantic memory after basal forebrain and fornix lesion

Marco Solcà

Semantic memory impairment is classically associated with lesion of the anterior temporal lobe. We report the case of a patient with severe semantic knowledge impairment and anterograde amnesia after bilateral ischemic lesion of the fornix and of the basal ...

2014

Implicit Affective Profiling of Subjects based on Physiological Data Coupling

Touradj Ebrahimi, Jean-Marc Vesin, Eleni Kroupi

Evidence from neuroscience and psychology supports the idea that synchronization among various sub-components of the organism is the key-point to emotional processes. This study investigates the way signals from the central nervous system interact with sig ...

2014

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