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The ankle is one of the most injured joint in the body. However, it remains a new field of study in biomedical orthopedics. With the increased life span, more people suffer from arthosis and joint problems. That is why the improvements done in arthroplasty ...
While human bone morphogenetic protein-2 (rhBMP-2) is a promising growth factor for bone regeneration, its clinical efficacy has recently shown to be below expectation. In order to improve the clinical translation of rhBMP-2, there exists strong motivation ...
Purpose. To assess the effect of external mechanical microstimuli of controlled magnitude on the microarchitecture of the peri-implant bone beds in rat tibiae. Materials and Methods. Tibiae of forty rats were fitted with two transcutaneous titanium cylinde ...
The primary stability of cementless femoral components is crucial for the long-term success of total hip arthroplasty. The mechanisms which influence this stability are not yet well understood. However, mechanical environment in peri-implant tissue is know ...
Modification of bone implant materials with biofunctional surfaces that facilitate osteoblast adhesion and promote matrix mineralization is an attractive strategy to improve osseointegration. This manuscript discusses the preparation and properties of RGD ...
The initial stability of cementless femoral components is crucial for the long-term success of total hip arthroplasty. This has been reported in animal and clinical studies. Until now, the stability was evaluated by the measurement of relative micromotion ...
The ankle is a complex joint of the human body which is most often affected by trauma. Osteoarthritis is a joint disease that can require surgical intervention and when it affects the ankle there are two options to achieve pain relief. For years ankle fusi ...
The hip is one of the most injured joint in the body with ageing. Osteoarthritis and degenerative diseases often lead to the necessity of a total hip arthroplasty in order to reduce pain and increase mobility. The advantage of cementless implants resides i ...
Prophylactic vertebroplasty, the percutaneous injection of bone cement into a weak vertebral body (VB), has been shown to reinforce the bone and possibly to minimize fracture risks. Cement leakage is still a common occurrence that can cause severe complica ...
Developing a successful bone tissue engineering strategy entails translation of experimental findings to clinical needs. A major leap forward towards this goal is developing a quantitative tool to predict spatial and temporal bone formation in scaffold. We ...