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Bones generate electricity under pressure, and this electromechanical behavior is thought to be essential for bone’s self-repair and remodeling properties. The origin of this response is attributed to the piezoelectricity of collagen, which is the main str ...
Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...
Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...
Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...
Purpose of review The review aims at comprehensively discussing our current knowledge on bone metastases incidence in non-small cell lung cancer (NSCLC), their related complications as well as clinical impact in patients suffering from advanced disease. Re ...
Alzheimer's disease (AD) is a looming threat on an ever-ageing population, with devastating effects on the human intellect. A particular characteristic lesion - the extracellular amyloid plaque - accumulates in the brain of AD patients during the course of ...
Positron Emission Tomography (PET) aims at recovering the metabolic activity of an organ of interest. Established algorithms implemented in contemporary PET scans are based on an approximation of the inverse Radon transform, resulting in a suboptimal estim ...
Purpose: Most effective antitumor therapies induce tumor cell death. Non-invasive, rapid and accurate quantitative imaging of cell death is essential for monitoring early response to antitumor therapies. To facilitate this, we previously developed a biocom ...
Locally applied bisphosphonates, such as Zoledronate, have been shown in several studies to inhibit peri-implant bone resorption and recently to enhance peri-implant bone formation. Studies have also demonstrated positive effects of hydroxyapatite particle ...
Bone marrow-derived myeloid cells can accumulate within tumors and foster cancer outgrowth. Local immune-neoplastic interactions have been intensively investigated, but the contribution of the systemic host environment to tumor growth remains poorly unders ...