Concept
Nucleic acid secondary structure
Related publications (135)
A generalized profile syntax for biomolecular sequence motifs and its function in automatic sequence interpretation
A general syntax for expressing biomolecular sequence motifs is described, which will be used in future releases of the PROSITE data bank and in a similar collection of nucleic acid sequence motifs currently under development. The central part of the synta ...
1994Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides
This paper reports the synthesis of rationally designed polypeptides that catalyze the decarboxylation of oxaloacetate via an imine intermediate. The authors det. the secondary structures of the polypeptides by two-dimensional NMR spectroscopy. The authors ...
1993Partial characterization of natural and recombinant human soluble CD23
The purification to homogeneity of an active soluble 25 kDa fragment of CD23, produced in insect cells using the baculovirus expression system, is described. Peptide mapping and analysis by Edman degradation and mass spectrometry permitted partial characte ...
1992Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica
Françoise Gisou van der Goot Grunberg
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was isolated. The cDNA-deduced amino acid sequence revealed a putativ ...
1992Novel approaches to template assembled synthetic proteins (TASP)
A report from a symposium on the prepn. and conformation of template assembled synthetic proteins, consisting of lysine-contg. cyclic decapeptide with four helical peptides attached via the lysine e-amino groups. Conformational studies show a clear templat ...
1991RETENTION BEHAVIOR OF A TEMPLATE-ASSEMBLED SYNTHETIC PROTEIN AND ITS AMPHIPHILIC BUILDING-BLOCKS ON REVERSED-PHASE COLUMNS
The retention behaviour of a six-helix bundle template-assembled synthetic protein (TASP) molecule and its amphiphilic building blocks was investigated. The TASP consists of a circular template, cyclo(1-12)[KG]6, and six identical potentially alpha-helical ...
1991PROTEIN DESIGN - TEMPLATE-ASSEMBLED SYNTHETIC PROTEINS
The introduction of the template-assembled synthetic protein (TASP) concept for the de novo design of proteins has provided a very powerful new tool for the construction of artificial tertiary structures. TASPs are constructed by the covalent attachment of ...
1991A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm
Expression of the human transferrin receptor (hTR) and its mRNA is strongly induced by iron deprivation. By measuring transcription elongation rates, levels of hTR-specific nuclear RNA, and mRNA half-lives, we found this regulation to occur posttranscripti ...
1988The secondary structure of bacteriorhodopsin determined by Raman and circular dichroism spectroscopy
The secondary structure of bacterio-opsin (BO), the retinal free protein-component of bacteriorhodopsin (BR), was detd. by Raman spectroscopy. Addnl. CD measurements revealed only negligible conformational differences between BO in apomembranes and BR in p ...
1987Nucleotide sequence and transcriptional startpoint of the glpT gene of Escherichia coli: extensive sequence homology of the glycerol-3-phosphate transport protein with components of the hexose-6-phosphate transport system
The nucleotide sequences of the glpT gene of Escherichia coli and its regulatory region have been elucidated and the primary structure of the glycerol-3-phosphate transport protein deduced. Extensive amino acid sequence homology was found with two other cy ...
1987