Publications related to Psychotic depression

Visual masking and schizophrenia: enhancement deficit 200 ms after stimulus onset

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Janir Nuno Ramos Antunes Da Cruz

Masking is strongly deteriorated in schizophrenia patients and to a lesser extent in their healthy relatives. For this reason, masking is a good endophenotype. Here, we show the EEG correlates of masking across the schizophrenia continuum in order to tackl ...

2018

Visual backward masking and the schizophrenia spectrum: EEG correlates

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod

Schizophrenia is a heterogeneous disease strongly influenced by genetic factors. We have previously shown that visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia (Chkonia et al., 2010). Importantly, not only patients but also ...

2017

Altered structural network architecture is predictive of the presence of psychotic symptoms in patients with 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Marie Schaer, Maria Carmela Padula

22q11.2 deletion syndrome (22q11DS) represents a homogeneous model of schizophrenia particularly suitable for the search of neural biomarkers of psychosis. Impairments in structural connectivity related to the presence of psychotic symptoms have been repor ...

Elsevier Sci Ltd2017

Electrophysiological correlates of visual backward masking in first-episode psychosis

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod

Schizophrenia is a heterogeneous disorder and among other symptoms, patients have important visual impairments. Visual paradigms are therefore important tools to investigate the mechanisms of schizophrenia. We have previously shown that visual backward mas ...

2017

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Dimitri Nestor Alice Van De Ville, Maude Schneider, Marie Schaer, Jonas Richiardi, Fikret Isik Karahanoglu

The 22q11.2 deletion syndrome (22q11DS) is associated with cognitive impairments and a 41% risk of developing schizophrenia. While several studies performed on patients with 22q11DS showed the presence of abnormal functional connectivity in this syndrome, ...

Elsevier Masson2016

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression

Pierre Magistretti, Jean-René Cardinaux

Recent studies implicate the arginine-decarboxylation product agmatine in mood regulation. Agmatine has antidepressant properties in rodent models of depression, and agmatinase (Agmat), the agmatine-degrading enzyme, is upregulated in the brains of mood di ...

Nature Publishing Group2016

Impaired cognitive functioning in first-episode patients

Michael Herzog, Maya Roinishvili

The first psychotic episode is an important period for prevention of cognitive and social deterioration in schizophrenia. Cognitive deficits are of particular interest since they are evident even before a proper diagnosis can be made. Interestingly, there ...

Sage Publications Ltd2016

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Pierre Magistretti, Jean-René Cardinaux

Major depression is a highly complex disabling psychiatric disorder affecting millions of people worldwide. Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these medications. A better ...

Elsevier2016

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

Pierre Magistretti, Aurélie Delacrétaz

Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long ...

Public Library of Science2015

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Psychotic depression

Visual masking and schizophrenia: enhancement deficit 200 ms after stimulus onset

Visual backward masking and the schizophrenia spectrum: EEG correlates

Altered structural network architecture is predictive of the presence of psychotic symptoms in patients with 22q11.2 deletion syndrome

Electrophysiological correlates of visual backward masking in first-episode psychosis

Backward masking performance in patients with functional psychoses

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression

Impaired cognitive functioning in first-episode patients

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

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Visual backward masking and the schizophrenia spectrum: EEG correlates

Electrophysiological correlates of visual backward masking in first-episode psychosis

Visual masking and schizophrenia: enhancement deficit 200 ms after stimulus onset

Large-scale functional network reorganization in 22q11.2 deletion syndrome revealed by modularity analysis

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

Backward masking performance in patients with functional psychoses

Impaired cognitive functioning in first-episode patients

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Altered structural network architecture is predictive of the presence of psychotic symptoms in patients with 22q11.2 deletion syndrome

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression