Concept

Aqueous two-phase system

Summary
Aqueous biphasic systems (ABS) or aqueous two-phase systems (ATPS) are clean alternatives for traditional organic-water solvent extraction systems. ABS are formed when either two polymers, one polymer and one kosmotropic salt, or two salts (one chaotropic salt and the other a kosmotropic salt) are mixed at appropriate concentrations or at a particular temperature. The two phases are mostly composed of water and non volatile components, thus eliminating volatile organic compounds. They have been used for many years in biotechnological applications as non-denaturing and benign separation media. Recently, it has been found that ATPS can be used for separations of metal ions like mercury and cobalt, carbon nanotubes, environmental remediation, metallurgical applications and as a reaction media. Introduction In 1896, Beijerinck first noted an 'incompatibility' in solutions of agar, a water-soluble polymer, with soluble starch or gelatine. Upon mixing, they separated into two
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