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Heart rate variability at bedtime predicts subsequent sleep features

Fiorenzo Artoni, Maria Paola Tramonti Fantozzi

Getting enough sleep during the night is important for preventing adverse short- and long-term health outcomes. The sympathetic-parasympathetic autonomic balance, characteristics of the pre-bed time resting period, correlates with sleep efficiency. We inve ...

IEEE2019

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Nicotine increases sleep spindle activity

Christian O'Reilly

Studies have shown that both nicotine and sleep spindles are associated with enhanced memorisation. Further, a few recent studies have shown how cholinergic input through nicotinic and muscarinic receptors can trigger or modulate sleep processes in general ...

WILEY2019

Tissue-specific circadian transcriptional regulation

Jake Yeung

Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-hour day, which requires extensive gene expression rhythms targeted to the right ...

EPFL2019

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Hasan Pezeshgi Modarres, Sha Li, Cyril Mikhail

Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral hypothalamus and play important roles in sleep, metabolism, reward, and motivation. Loss of HCRT (ligands or receptors) causes the sleep ...

National Academy of Sciences2019

Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health

Frédéric Bruno Martin Gachon

Chrono-nutrition is an emerging research field in nutritional epidemiology that encompasses 3 dimensions of eating behavior: timing, frequency, and regularity. To date, few studies have investigated how an individual's circadian typology, i.e., one's chron ...

OXFORD UNIV PRESS2019

How to assess alerting effects of daylight at the workplace? Learnings from semi-controlled studies

Marilyne Andersen, Victoria Eugenia Soto Magán

Daylight, in which we evolved, is naturally rich in the blue component of the spectrum and has key properties when it comes to impacts on body functioning. Current lifestyles are driving the emergence of a 24-hour society that spends most of the time indoo ...

2019

Can Daytime Napping Assist the Process of Skills Acquisition After Stroke?

Friedhelm Christoph Hummel, Winifried Backhaus

Acquisition and reacquisition of skills is a main pillar of functional recovery after stroke. Nighttime sleep has a positive influence on motor learning in healthy individuals, whereas the effect of daytime sleep on neuro-rehabilitative training and relear ...

2018

Analysis of U-Shape Patterns in RR-Interval Time Series During Sleep

Jean-Marc Vesin, Grégoire Millet, Sasan Yazdani, Alexandre Thierry Robert Cherqui

The proposed study investigates a phenomenon, defined as "U-patterns", that takes place in the RR-interval time series during sleep. These patterns are defined as a U-shaped decrease-increase in the RR-intervals, with a duration of 20 to 40 seconds with a ...

IEEE2018

Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus)

Stéphane Joost, Idris Guessous, Rebecca Himsl

INTRODUCTION: Daytime sleepiness is highly prevalent in the general adult population and has been linked to an increased risk of workplace and vehicle accidents, lower professional performance and poorer health. Despite the established relationship between ...

2018

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Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

National Academy of Sciences2019

Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus)

Stéphane Joost, Idris Guessous, Rebecca Himsl

2018

How to assess alerting effects of daylight at the workplace? Learnings from semi-controlled studies

Marilyne Andersen, Victoria Eugenia Soto Magán

2019