Concept
Immunization
Related publications (26)
Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization
Philippe Colin, Aleksandar Antanasijevic
Neutralizing antibodies (NAbs) to multiple epitopes on the HIV-1-envelope glycoprotein (Env) have been isolated from infected persons. The potency of NAbs is measured more often than the size of the persistent fraction of infectivity at maximum neutralizat ...
San Francisco2023Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study
Jacques Fellay, Christian Axel Wandall Thorball
Leukocyte count is associated with coronary artery disease (CAD) events in the general population. Here we show that leukocytes are independently associated with CAD events in people with HIV in Switzerland, after adjusting for traditional and HIVrelated r ...
OXFORD UNIV PRESS INC2023Immunizing Systems from Distant Failures by Limiting Lamport Exposure
Bryan Alexander Ford, Cristina Basescu
Failures far away from a user should intuitively be less likely to affect that user. Today's ecosystem miserably fails this test, however, despite high-availability best practices. Correlated and cascading failures – triggered by misconfigurations, bugs, a ...
Association for Computing Machinery2021On the exploration of novel methodological approaches for immunogen design: case studies in influenza and hepatitis C
Proteins are fundamental components in biological systems and crucial for a variety of biological functions. Over the last decades, significant progress in structural biology has facilitated the study of proteins and their interactions with molecular partn ...
EPFL2021Contact networks across ages: computational analysis of epidemiological dynamics
For decades mathematical modeling in epidemiology has helped understanding the dynamics of infectious diseases, as well as describe possible intervention scenarios to prevent and control them. However, such models were relying on several assumptions, such ...
EPFL2020Hexachlorobenzene exerts genotoxic effects in a humpback whale cell line under stable exposure conditions
Humpback whales, like other polar wildlife, accumulate persistent organic pollutants. In Southern hemisphere populations, hexachlorobenzene (HCB) dominates the contaminant profiles. HCB is linked to a variety of health effects and is classified as a group ...
ROYAL SOC CHEMISTRY2019Interplay between cost and benefits triggers nontrivial vaccination uptake
Paolo De Los Rios, Alessio Vincenzo Cardillo
The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total immunization is not ...
2018Benefit of vaccination in protecting the departments of Grand’Anse, Ouest and Sud against a potential second epidemic wave of cholera
Andrea Rinaldo, Enrico Bertuzzo, Flavio Finger, Damiano Pasetto
In a previous report, we presented model projections based on data available up to epi-week 43 (ending Oct-29). These projections suggested that, due to anticipated heavy rainfalls at the end of November, a second peak of cholera might be observed in early ...
Epicentre2016New immunomodulatory roles of lymphatic endothelium and implications for immunotherapy
The lymphatic system serves a critical role in fluid homeostasis, lipid metabolism and immune surveillance. The growing appreciation of its implication in various diseases challenges the conventional view of lymphatics as a passive transport system. Tradit ...
EPFL2016Encapsulated Cellular Implants for Recombinant Protein Delivery and Therapeutic Modulation of the Immune System
Bernard Schneider, Aurélien Lathuilière
Ex vivo gene therapy using retrievable encapsulated cellular implants is an effective strategy for the local and/or chronic delivery of therapeutic proteins. In particular, it is considered an innovative approach to modulate the activity of the immune syst ...
MDPI2015