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In this work we address the use of realtime cortical recordings for the generation of coherent, reliable and robust motor activity in spinal-lesioned animals through selective intraspinal microstimulation (ISMS). The spinal cord of adult rats was hemisecti ...
Independent use of both hands is characteristic of human action in daily life. By nature, however, in-phase bimanual movements, for example clapping, are easier to accomplish than anti-phase movements, for example playing the piano. It is commonly agreed t ...
During the procedure of prism adaptation, subjects execute pointing movements to visual targets under a lateral optical displacement: as consequence of the discrepancy between visual and proprioceptive inputs, their visuo-motor activity is characterized by ...
Motor imagery (MI) brain-computer interfaces (BCIs) translate a subject’s motor intention to a command signal. Most MI BCIs use power features in the mu or beta rhythms, while several results have been reported using a measure of phase synchrony, the phase ...
Despite many efforts, balance control of humanoid robots in the presence of unforeseen external or internal forces has remained an unsolved problem. The difficulty of this problem is a consequence of the high dimensionality of the action space of a humanoi ...
Multiple motor function and strength assessment tools exist for the evaluation of neuromuscular diseases, but most do not directly assess functional ability in the patients' daily physical activity in their home environment. In this study our aim was to as ...
Gilles de la Tourette syndrome is a neuropsychiatric disorder in which cortical disinhibition has been proposed as a pathophysiological mechanism involved in the generation of tics. Tics are typically reduced during task performance and concentration. How ...
Dealing with uncertainties and lack of knowledge about problems and situations, there is a perpetual difficulty to evaluate the situations and action values in all time steps. On the other hand, the design of critics which delicately guide the agent even w ...
Monaco V, Ghionzoli A, Micera S. Age-related modifications of muscle synergies and spinal cord activity during locomotion. J Neurophysiol 104: 2092-2102, 2010. First published August 4, 2010; doi:10.1152/jn.00525.2009. Recent findings have shown that neura ...
Huntington's disease (HD), caused by a mutation of the corresponding gene encoding the protein huntingtin (htt), is characterized by progressive deterioration of cognitive and motor functions, paralleled by extensive loss of striatal neurons. At the cellul ...
