Publications related to Sodium channel

Prospects of Observing Ionic Coulomb Blockade in Artificial Ion Confinements

Aleksandra Radenovic, Andrey Chernev, Sanjin Marion

Nanofluidics encompasses a wide range of advanced approaches to study charge and mass transport at the nanoscale. Modern technologies allow us to develop and improve artificial nanofluidic platforms that confine ions in a way similar to single-ion channels ...

MDPI2020

Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes

Stefano Zamuner, Margherita Marchi

Applications of machine learning and graph theory techniques to neuroscience have witnessed an increased interest in the last decade due to the large data availability and unprecedented technology developments. Their employment to investigate the effect of ...

NATURE RESEARCH2020

Enhancing the Signaling of GPCRs via Orthosteric Ions

Horst Vogel, Shuguang Yuan

G protein-coupled receptors play essential roles in cellular processes such as neuronal signaling, vision, olfaction, tasting, and metabolism. As GPCRs are the most important drug targets, understanding their interactions with ligands is of utmost importan ...

AMER CHEMICAL SOC2020

Auditing Radicalization Pathways on YouTube

Robert West, Manoel Horta Ribeiro

Non-profits, as well as the media, have hypothesized the existence of a radicalization pipeline on YouTube, claiming that users systematically progress towards more extreme content on the platform. Yet, there is to date no substantial quantitative evidence ...

ASSOC COMPUTING MACHINERY2020

Sampling and Reconstruction of Bandlimited Signals with Multi-Channel Time Encoding

Martin Vetterli, Adam James Scholefield, Karen Adam

Sampling is classically performed by recording the amplitude of the input at given time instants; however, sampling and reconstructing a signal using multiple devices in parallel becomes a more difficult problem to solve when the devices have an unknown sh ...

2020

GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

Sean Lewis Hill, Christian Andreas Rössert, Bas-Jan Zandt, Steven Petrou

The binding of GABA (gamma-aminobutyric acid) to extrasynaptic GABA(A) receptors generates tonic inhibition that acts as a powerful modulator of cortical network activity. Despite GABA being present throughout the extracellular space of the brain, previous ...

NATL ACAD SCIENCES2020

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

Stewart Cole, Florence Pojer, Jérémie Piton

The EspB protein of Mycobacterium tuberculosis is a 60 kDa virulence factor, implicated in conjugation and exported by the ESX-1 system of which it may also be a component. Previous attempts to obtain high-resolution maps of EspB by cryo-electron microscop ...

2020

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Mohamed Adbelalim Gadalla

Hemagglutinin (HA), a glycoprotein of Influenza A viruses and its proton channel M2 are site-specifically modified with fatty acids. Whereas two cysteines in the short cytoplasmic tail of HA contain only palmitate, stearate is exclusively attached to one c ...

PORTLAND PRESS LTD2020

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Sodium channel

Prospects of Observing Ionic Coulomb Blockade in Artificial Ion Confinements

Towards artificial mechanosensing

Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes

Enhancing the Signaling of GPCRs via Orthosteric Ions

Suspended microchannel resonators for Biosensing applications

Auditing Radicalization Pathways on YouTube

Sampling and Reconstruction of Bandlimited Signals with Multi-Channel Time Encoding

GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

Graph Chatbot

Chat with Graph Search

Prospects of Observing Ionic Coulomb Blockade in Artificial Ion Confinements

Towards artificial mechanosensing

Sampling and Reconstruction of Bandlimited Signals with Multi-Channel Time Encoding

Enhancing the Signaling of GPCRs via Orthosteric Ions

Suspended microchannel resonators for Biosensing applications

Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes

Auditing Radicalization Pathways on YouTube

GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20