Concept
Generic drug
Related lectures (33)
Preclinical Animal Models: Selection & Rationale
Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.
Pharmacokinetic & Pharmacodynamic Studies
Discusses the importance of assessing PK/PD relationships in drug development and the use of multiple PD biomarkers.
Small Molecule Drugs: Genetic Diseases
Delves into the molecular basis of genetic diseases, discussing specific examples like Phenylketonuria and Haemophilia A, and the development of small molecule drugs for genetic disorders.
Protein Induced Degradation: Druggability Strategy
Explores protein-induced degradation to enhance target druggability and the use of PROTACS in drug development.
Introduction: small molecule drugs for cancer
Introduces small molecule drugs for cancer treatment, covering drug discovery, mechanisms of action, and historical development of anti-cancer agents.
Innovation Appropriability
Explores innovation appropriability, strategies for exclusivity, pricing challenges, and the impact of patents on innovation.
Neurotransmitters: Receptors and Effects
Explores major neurotransmitters, their effects, drug therapy, and receptor mechanisms in brain function.
Drug Delivery: Nanoparticles and Biomaterials
Explores design parameters, nanomaterials, natural barriers, stimuli responsiveness, and engineering possibilities in drug delivery systems.
Interrogating SAR in Medical Chemistry
Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.
Infectious Diseases: Small Molecule Drugs
Explores small molecule drugs for infectious diseases, covering global mortality rates, viral and bacterial injuries, antiviral and antibacterial agents, and the development of COX2 inhibitors.