Concept
Antibiotic sensitivity testing
Related publications (139)
Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform
Sandor Kasas, Anthony Vocat, Gino Cathomen, Eric Delarze, Florian Tagini, Laura Munch
Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests (ASTs). Accelerated ASTs can identify effective antibiotics for t ...
Nature Portfolio2024Homogeneous vs. heterogeneous photo-Fenton elimination of antibiotic-resistant bacteria bearing intracellular or extracellular resistance: Do resistance mechanisms interfere with disinfection pathways?
César Pulgarin, Stefanos Giannakis, Truong-Thien Melvin Le, Jérémie Decker
The present study aimed to fill the knowledge gap between the implications of intracellular and extracellular antibiotic resistance mechanisms may inflict on the inactivation pathways of the photo-Fenton process under mild conditions. It was thus designed ...
London2024Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics
Camille Véronique Bernadette Goemans, Florian Huber
By acquiring or evolving resistance to one antibiotic, bacteria can become resistant to a second one, due to shared underlying mechanisms. This is called cross-resistance (XR) and further limits therapeutic choices. The opposite scenario, in which initial ...
2024Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii
Melanie Blokesch, Loriane Bader, Mary-Claude Croisier-Coeytaux, Nicolas Olmo Flaugnatti
The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with th ...
2024Machine learning method for the classification of the state of living organisms' oscillations
Sandor Kasas, María Inés Villalba
The World Health Organization highlights the urgent need to address the global threat posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to antibiotics and their virulence state is crucial for the effective treatmen ...
Frontiers Media Sa2024Implementing water recirculation in a novel portable plasma-activated water reactor enhances antimicrobial effect against Escherichia coli
Ivo Furno, Alan Howling, Fabio Avino, Rita Agus, Brayden Graham Myers, Lorenzo Ibba, Leonardo Zampieri
The need for sustainable and reliable decontamination methods is driven by concerns regarding antibiotic resistance, as well as environmental and cost -efficiency challenges associated with traditional methods. Plasmaactivated water (PAW) holds significant ...
Elsevier Science Sa2024Simple optical nanomotion method for single-bacterium viability and antibiotic response testing
Sandor Kasas, María Inés Villalba, Allan Bonvallat, Eugenia Rossetti
Antibiotic resistance is nowadays a major public health issue. Rapid antimicrobial susceptibility tests (AST) are one of the options to fight this deadly threat. Performing AST with single-cell sensitivity that is rapid, cheap, and widely accessible, is ch ...
NATL ACAD SCIENCES2023Antimicrobial susceptibility testing with integrated photonic crystal optical tweezers
The abusive use of antimicrobial drugs during the last eighty years has favoured the natural selection of resistant pathogens able to neutralise drugs efficiently. Nowadays, antimicrobial resistance contributes to millions of deaths yearly, threatens the e ...
EPFL2023A Rapidly Responsive Sensor for Wireless Detection of Early and Mature Microbial Biofilms
Hubert Girault, Wanderson Oliveira Da Silva, Andreas Stephan Lesch, Bhawna Nagar
Biofilm-associated infections, which are able to resist antibiotics, pose a significant challenge in clinical treatments. Such infections have been linked to various medical conditions, including chronic wounds and implant-associated infections, making the ...
WILEY-V C H VERLAG GMBH2023DNA modifications impact natural transformation of Acinetobacter baumannii
Melanie Blokesch, Nicolas Jean Philippe Guex, Christian Iseli, Alexandre Lemopoulos, Nina Vesel
Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A. baumannii, natural competence for transformation, one of the primary modes o ...
2023