Concept
Mechanobiology
Related publications (8)
Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology
Mahmut Selman Sakar, Erik Mailand, Nikolaos Bouklas, Fazil Emre Uslu
Mechanobiology explores how forces regulate cell behaviors and what molecular machinery are responsible for the sensing, transduction, and modulation of mechanical cues. To this end, probing of cells cultured on planar substrates has served as a primary ex ...
2021Wireless soft microscale actuators and robotic devices to study mechanobiology
Raquel Filipa Penacho Parreira
Tissues morphogenesis and homeostasis involve the spatiotemporal regulation of mechanics at multiple scales. Characterization of mechanical properties of biological systems as well as investigating the effects of mechanical forces on biological function ar ...
EPFL2021The role of mechanical hysteresis source in mechanical and mechanobiological performances of load-bearing biomaterials
Naser Nasrollahzadeh Mamaghani
Tissue engineering is a promising approach for articular cartilage regeneration as no satisfactory treatment is actually available for cartilage, partly due to the very limited self-healing capability of this tissue. To successfully induce a cartilaginous ...
EPFL2019Intrinsic viscoelasticity increases temperature in knee cartilage under physiological loading
Dominique Pioletti, Philippe Abdel Sayed, Mohamadreza Nassajian Moghadam
Metabolism of proteoglycans and hyaluronic acid has been shown to be temperature- dependent in cartilage explants, with optimal anabolic effects between 36 1C and 38 1C. At rest, the temperature of human knee has a value of around 33 1C. We aim to show in ...
Elsevier2014