Concept
Origin and function of meiosis
Related publications (7)
The role of Schizosaccharomyces pombe dma1 in spore formation during meiosis
Viesturs Simanis, Andrea Krapp, Elena Cano
Meiosis is a specialised form of the cell cycle that gives rise to haploid gametes. In Schizosaccharomyces pombe, the products of meiosis are four spores, which are formed by encapsulation of the four meiosis II nuclei within the cytoplasm of the zygote pr ...
2010The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice
Johan Auwerx, Kristina Schoonjans
Studies in rodents have shown that male sexual function can be disrupted by fetal or neonatal administration of compounds that alter endocrine homeostasis, such as the synthetic nonsteroidal estrogen diethylstilbestrol (DES). Although the molecular basis f ...
American Society for Clinical Investigation2009The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice
Johan Auwerx, Kristina Schoonjans
The small heterodimer partner (SHP) is an atypical nuclear receptor known mainly for its role in bile acid homeostasis in the enterohepatic tract. We explore here the role of SHP in the testis. SHP is expressed in the interstitial compartment of the adult ...
2007Zyg-11 and cul-2 regulate progression through meiosis II and polarity establishment in C. elegans
The mechanisms that ensure coupling between meiotic cell cycle progression and subsequent developmental events, including specification of embryonic axes, are poorly understood. Here, we establish that zyg-11 and the cullin cul-2 promote the metaphase-to-a ...
2004roughex is a dose-dependent regulator of the second meiotic division during Drosophila spermatogenesis
During spermatogenesis, germ cells execute two meiotic divisions, then withdraw from the cell cycle and initiate postmeiotic differentiation. We show that the gene roughex (rux) is a dose-dependent regulator of meiosis II during Drosophila spermatogenesis. ...
1994Maternal modulation of the inheritable meiosis I error Dipl I in mouse oocytes is associated with the type of mitochondrial DNA
The ovulation of diploid oocytes, abnormally arrested at or during the first meiotic division, is an inheritable trait (DiplI) in mice and modulated by a maternally transmitted factor. By repeated backcrossing, mouse strains with identical nuclear encoded ...
1988