Concept

Epithelium

Related publications (164)

Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells

Matthias Lütolf, Stefan Kobel, Samy Gobaa

Microfluidic technology has been successfully applied to isolate very rare tumor-derived epithelial cells (circulating tumor cells, CTCs) from blood with relatively high yield and purity, opening up exciting prospects for early detection of cancer. However ...

2012

Loss of Cutaneous TSLP-Dependent Immune Responses Skews the Balance of Inflammation from Tumor Protective to Tumor Promoting

Freddy Radtke, Ute Koch, Craig Nowell, Matteo Di Piazza

Inflammation can promote or inhibit cancer progression. In this study we have addressed the role of the proinflammatory cytokine thymic stromal lymphopoietin (TSLP) during skin carcinogenesis. Using conditional loss- and gain-of-function mouse models for N ...

Elsevier2012

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut

Bruno Lemaitre, Sveta Chakrabarti

Typically, immune responses control the pathogen, while repair and stress pathways limit damage caused by pathogenesis. The relative contribution of damage to the outcome of pathogenesis and the mechanistic links between the immune and repair pathways are ...

Cell Press2012

Prospective and retrospective motion correction in diffusion magnetic resonance imaging of the human brain

Rolf Gruetter, Tobias Kober

Diffusion-weighting in magnetic resonance imaging (MRI) increases the sensitivity to molecular Brownian motion, providing insight in the micro-environment of the underlying tissue types and structures. At the same time, the diffusion weighting renders the ...

Elsevier2012

Clinical application of autologous epithelial stem cells in disorders of squamous epithelia

Yann Barrandon, Nicolas Grasset

Epidermis and epithelia lining the ocular surface, the oral cavity, the pharynx, the oesophagus, the larynx, and the vagina, called stratified squamous epithelia (SSE), contain stem/progenitor cells that support renewal and repair. Under appropriate condit ...

Humana Press2011

Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells

Léa Chanson

Loss of organization is a principle feature of cancers; therefore it is important to understand how normal adult multilineage tissues, such as bilayered secretory epithelia, establish and maintain their architectures. The self-organization process that dri ...

2011

Boundary formation and maintenance in tissue development

Andrew Charles Oates

The formation and maintenance of boundaries between neighbouring groups of embryonic cells is vital for development because groups of cells with distinct functions must often be kept physically separated. Furthermore, because cells at the boundary often ta ...

2011

Neurogenin3 Initiates Stepwise Delamination of Differentiating Endocrine Cells During Pancreas Development

Anne Grapin-Botton, Mathieu Gouzi, Yung Hae Kim, Keiichi Katsumoto

During development, pancreatic endocrine cells are specified within the pancreatic epithelium. They subsequently delaminate out of the epithelium and cluster in the mesenchyme to form the islets of Langerhans. Neurogenin3 (Ngn3) is a transcription factor r ...

2011

High hopes for RANKL: will the mouse model live up to its promise?

Cathrin Brisken, Tamara Tanos

The steroid hormones, estrogens and progesterone are key drivers of postnatal breast development and are linked to breast carcinogenesis. Experiments in the mouse mammary gland have revealed that they rely on paracrine factors to relegate their signal loca ...

BioMed Central2011

Potential of Ultraviolet Wide-Field Imaging and Multiphoton Microscopy for Analysis of Dehydroergosterol in Cellular Membranes

Daniel Sage

Dehydroergosterol (DHE) is an intrinsically fluorescent sterol with absorption/emission in the ultraviolet (UV) region and biophysical properties similar to those of cholesterol. We compared the potential of UV-sensitive low-light-level wide-field (UV-WF) ...

Wiley2011

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