Causes of schizophrenia

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The complexity of schizophrenia: a battery of tests

Michael Herzog

Schizophrenia research has focused on single mechanisms mainly. Classically, a paradigm is chosen, such as a cognitive or perceptual test. The outcome is usually that schizophrenia patients perform worse than controls. Substantial research is then spent to ...

2016

Visual masking & schizophrenia

Michael Herzog

Visual masking is a frequently used tool in schizophrenia research. Visual masking has a very high sensitivity and specificity and masking paradigms have been proven to be endophenotypes. Whereas masking is a powerful technique to study schizophrenia, the ...

2015

Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients

Jean-Philippe Thiran, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Kim Do, Aline Monin, Patric Hagmann, Philipp Baumann

Schizophrenia pathophysiology implies both abnormal redox control and dysconnectivity of the prefrontal cortex, partly related to oligodendrocyte and myelin impairments. As oligodendrocytes are highly vulnerable to altered redox state, we investigated the ...

Nature Publishing Group2015

Regional cortical volumes and congenital heart disease: a MRI study in 22q11.2 deletion syndrome

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer, Maude Schneider

Children with congenital heart disease (CHD) who survive surgery often present impaired neurodevelopment and qualitative brain anomalies. However, the impact of CHD on total or regional brain volumes only received little attention. We address this question ...

2010

Dysconnection Topography in Schizophrenia Revealed with State-Space Analysis of EEG

Martin Hasler, Oscar De Feo, Kim Do, Reto Meuli, Mahdi Jalili

Background The dysconnection hypothesis has been proposed to account for pathophysiological mechanisms underlying schizophrenia. Widespread structural changes suggesting abnormal connectivity in schizophrenia have been imaged. A functional counterpart of t ...

2007

Duration and not strength of activation in temporo-parietal cortex positively correlates with schizotypy

Olaf Blanke, Christine Mohr

Impaired self- and own body processing in patients with schizophrenia and individuals along the schizophrenia spectrum have been associated with dysfunctional cortical activation at the temporo-parietal junction. Here we investigated whether strength or du ...

Elsevier2007

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