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Tissue engineering

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Tissue engineering

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Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes

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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)