Publications related to Cardiac skeleton

Efficient approximation of cardiac mechanics through reduced-order modeling with deep learning-based operator approximation

Reducing the computational time required by high-fidelity, full-order models (FOMs) for the solution of problems in cardiac mechanics is crucial to allow the translation of patient-specific simulations into clinical practice. Indeed, while FOMs, such as th ...

Hoboken2023

Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan

Nikolaos Stergiopoulos, Augusto Martins Lima, Valeria Romina Martinez

Background: Angiotensin II receptor blockers were designed as therapeutic agents to block the binding site of the angiotensin II receptor type 1 (AT1R). Methodology: The structure of telmisartan was modified by coordination to the biometal Zn(II), resultin ...

FUTURE SCI LTD2020

Hemodynamics of ageing, ventricular-arterial coupling and noninvasive assessment of key hemodynamical and cardiac quantities

Stamatia Zoi Pagoulatou

Ageing is a natural process that affects both the anatomical and functional properties of the cardiovascular system and alters the coupling characteristics between the heart and the aorta. These alterations may predispose the cardiovascular system in the d ...

EPFL2020

Complex blood flow patterns in an idealized left ventricle: A numerical study

Alfio Quarteroni, Anna Tagliabue

In this paper, we study the blood flow dynamics in a three-dimensional (3D) idealized left ventricle of the human heart whose deformation is driven by muscle contraction and relaxation in coordination with the action of the mitral and aortic valves. We pro ...

Amer Inst Physics2017

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Alfio Quarteroni, Luca Dede', Anna Tagliabue

In this paper, we study the blood flow dynamics in a three-dimensional (3D) idealized left ventricle of the human heart whose deformation is driven by muscle contraction and relaxation in coordination with the action of the mitral and aortic valves. We pro ...

MATHICSE2017

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Johan Auwerx, Julien Weber

Sirtuin 3 (Sirt3) is an NAD(+)-dependent mitochondrial deacetylase associated with superoxide dismutase 2 (SOD2)-mediated protection from oxidative stress. We have reported accelerated weight gain and impaired metabolic flexibility in atherosclerotic Sirt3 ...

Springer2016

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Jean-Marc Vesin, Adrian Luca, Vincent Jacquemet

Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...

2016

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Jean-Marc Vesin, Adrian Luca, Vincent Jacquemet

Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...

Oxford Univ Press2016

Fluid-structure interaction simulations of cerebral arteries modeled by isotropic and anisotropic constitutive laws

Alfio Quarteroni, Simone Deparis, Luca Dede', Paolo Tricerri, Adélia Sequeira

This paper considers numerical simulations of fluid-structure interaction (FSI) problems in hemodynamics for idealized geometries of healthy cerebral arteries modeled by both nonlinear isotropic and anisotropic material constitutive laws. In particular, it ...

Springer Verlag2015

Improved temporal resolution for functional studies with reduced number of segments with three-dimensional echo planar imaging

Rolf Gruetter, Tobias Kober, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, Mayur Narsude

PURPOSE: To introduce a new k-space traversal strategy for segmented three-dimensional echo planar imaging (3D EPI) that encodes two partitions per radiofrequency excitation, effectively reducing the number excitations used to acquire a 3D EPI dataset by h ...

Wiley-Blackwell2014

Cardiac skeleton

Efficient approximation of cardiac mechanics through reduced-order modeling with deep learning-based operator approximation

Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan

Hemodynamics of ageing, ventricular-arterial coupling and noninvasive assessment of key hemodynamical and cardiac quantities

Complex blood flow patterns in an idealized left ventricle: A numerical study

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Fluid-structure interaction simulations of cerebral arteries modeled by isotropic and anisotropic constitutive laws

Improved temporal resolution for functional studies with reduced number of segments with three-dimensional echo planar imaging

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Efficient approximation of cardiac mechanics through reduced-order modeling with deep learning-based operator approximation

Hemodynamics of ageing, ventricular-arterial coupling and noninvasive assessment of key hemodynamical and cardiac quantities

Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Fluid-structure interaction simulations of cerebral arteries modeled by isotropic and anisotropic constitutive laws

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Improved temporal resolution for functional studies with reduced number of segments with three-dimensional echo planar imaging

Complex blood flow patterns in an idealized left ventricle: A numerical study