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Related publications (242)

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Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike

Petr Leiman, Christopher Browning

Bacteriophages with contractile tails and the bacterial type VI secretion system have been proposed to use a special protein to create an opening in the host cell membrane during infection. These proteins have a modular architecture but invariably contain ...

2012

Adding Meaning to Your Steps (Keynote Paper)

Stefano Spaccapietra, Christine Parent

Mobility data is becoming an important player in many application domains. Many techniques have been elaborated to extract statistical knowledge from the data sets gathering raw data tracks about the moving objects of interest to an application. These data ...

Springer-Verlag New York, Ms Ingrid Cunningham, 175 Fifth Ave, New York, Ny 10010 Usa2011

A silicon model of the inner hair cell

Yusuf Leblebici

In this paper we present an electrical model of the inner hair cell based on an improved mathematical model. The model is implemented in silicon in the current domain using translinear circuits. It improves on previous models by taking into consideration t ...

2011

Parallel Molecular Dynamics with Irregular Domain Decomposition

The spatial domain of Molecular Dynamics simulations is usually a regular box that be easily divided in subdomains for parallel processing. Recent efforts aimed at simulating complex biological systems, like the blood flow inside arteries, require the exec ...

Cambridge University Press2011

Extending the aerolysin family: from bacteria to vertebrates

Françoise Gisou van der Goot Grunberg, Mircea Ioan Iacovache

A number of bacterial virulence factors have been observed to adopt structures similar to that of aerolysin, the principal toxin of Aeromonas species. However, a comprehensive description of architecture and structure of the aerolysin-like superfamily has ...

Public Library of Science2011

Island-Based Adaptable Embedded System Design

David Atienza Alonso, Ivan Beretta

Nowadays, hardware devices are meant to host the execution of many complex, multi-core applications, whose functional and non-functional requirements vary according to the specific working domain. In this work, we propose a design methodology that combines ...

Institute of Electrical and Electronics Engineers2011

A Wideband Doubly-Sparse Approach For MITO Sparse Filter Estimation

Rémi Gribonval

We propose an approach for the estimation of sparse filters from a convolutive mixture of sources, exploiting the time-domain sparsity of the mixing filters and the sparsity of the sources in the time-frequency (TF) domain. The proposed approach is based o ...

IEEE2011

ERBIN is a new SARA-interacting protein: Competition between SARA and SMAD2 and SMAD3 for binding to ERBIN

Georgios Sflomos

SARA, an early endosomal protein, plays a key role in TGFβ signalling, as it presents SMAD2 and SMAD3 for phosphorylation by the activated TGFβ receptors. Here, we show that ERBIN is a new SARA-interacting protein that can be recruited by SARA to early end ...

Company of Biologists2011

Algorithms for the partitioned solution of weakly coupled fluid models for cardiovascular flows

Alfio Quarteroni, Simone Deparis, Adelmo Cristiano Innocenza Malossi

The main goal of this work is to devise robust iterative strategies to partition the solution of the Navier-Stokes equations in a three-dimensional (3D) domain, into non overlapping 3D subdomains, which communicate through the exchange of averaged/integrat ...

International Journal for Numerical Methods in Biomedical Engineering2011

Tg-aprotinin fusion proteins and matrices thereof

Peter Frey, Jeffrey Alan Hubbell, Kristen Lorentz

Fusion proteins containing a first domain and a second domain, where the first domain contains a crosslinkable substrate domain and the second domain contains a fibrinolysis inhibitor, are provided. In a preferred embodiment, the fibrinolysis inhibitor is ...

2011