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Concept
Plant secondary metabolism
Summary
Secondary metabolism produces a large number of specialized compounds (estimated 200,000) that do not aid in the growth and development of plants but are required for the plant to survive in its environment. Secondary metabolism is connected to primary metabolism by using building blocks and biosynthetic enzymes derived from primary metabolism. Primary metabolism governs all basic physiological processes that allow a plant to grow and set seeds, by translating the genetic code into proteins, carbohydrates, and amino acids. Specialized compounds from secondary metabolism are essential for communicating with other organisms in mutualistic (e.g. attraction of beneficial organisms such as pollinators) or antagonistic interactions (e.g. deterrent against herbivores and pathogens). They further assist in coping with abiotic stress such as increased UV-radiation. The broad functional spectrum of specialized metabolism is still not fully understood. In any case, a good balance between products of primary and secondary metabolism is best for a plant’s optimal growth and development as well as for its effective coping with often changing environmental conditions. Well known specialized compounds include alkaloids, polyphenols including flavonoids, and terpenoids. Humans use many of these compounds for culinary, medicinal and nutraceutical purposes.
Research into secondary plant metabolism primarily took off in the later half of the 19th century, however, there was still much confusion over what the exact function and usefulness of these compounds were. All that was known was that secondary plant metabolites were "by-products" of the primary metabolism and were not crucial to the plant's survival. Early research only succeeded as far as categorizing the secondary plant metabolites but did not give real insight into the actual function of the secondary plant metabolites. The study of plant metabolites is thought to have started in the early 1800s when Friedrich Willhelm Serturner isolated morphine from opium poppy, and after that new discoveries were made rapidly.
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