Publications related to Ectoderm

Reaction wavefront theory of notochord segment patterning

The vertebrate axis is segmented into repetitive structures, the vertebrae. In fish, these segmented structures are thought to form from the paraxial mesoderm and the adjacent notochord. Recent work revealed an autonomous patterning mechanism in the zebraf ...

FRONTIERS MEDIA SA2022

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance

Sebastian Maerkl, Shiyu Cheng, Ivan Istomin, Maria Lopez Malo, Amir Shahein, Evan James Olson

Binding to binding site clusters has yet to be characterized in depth, and the functional relevance of low-affinity clusters remains uncertain. We characterized transcription factor binding to low-affinity clusters in vitro and found that transcription fac ...

NATURE PORTFOLIO2022

What are you synching about? Emerging complexity of Notch signaling in the segmentation clock

Andrew Charles Oates, Olivier François Venzin

The Segmentation clock is a population of cellular genetic oscillators, located in the posterior of the elongating vertebrate embryo, that governs the rhythmic and sequential segmentation of the body axis into somites. Somites are blocks of cells that give ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Matthias Lütolf, Felix Naef, Yoji Tabata, Eric Paquet, François Réal Rivest, Ambroise Roger Vuaridel, Andrea Manfrin

Signaling centers, localized groups of cells that secrete morphogens, play a key role in early development and organogenesis by orchestrating spatial cell fate patterning. Here we present a microfluidic approach that exposes human pluripotent stem cell (hP ...

NATURE PUBLISHING GROUP2019

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

Daniel Alpern

TAF4 (TATA-binding protein-associated factor 4) and its paralogue TAF4b are components of the TFIID core module. We inactivated the murine Taf4a gene to address Taf4 function during embryogenesis. Here we show that Taf4a(-/-) embryos survive until E9.5 whe ...

Nature Publishing Group2016

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Friedrich Beermann

Background: Patent ductus arteriosus is a life-threatening condition frequent in premature newborns but also present in some term infants. Current mouse models of this malformation generally lead to perinatal death, not reproducing the full phenotypic spec ...

Public Library of Science2013

Performance study of a UWB antenna in proximity to a human arm

Anja Skrivervik, Nuno Miguel Faria Pires, Mohsen Koohestani

This letter studies the frequency- and time-domain performance of a recently developed printed coplanar-fed ultrawideband (UWB) monopole antenna aiming at predicting its behavior close to a human arm. The input reflection coefficient (|S11|) and fidelity f ...

Institute of Electrical and Electronics Engineers2013

Dual Lineage-Specific Expression of Sox17 During Mouse Embryogenesis

Marine Marie Kraus, Anne Grapin-Botton, Laurence Anne E Lemaire

Sox17 is essential for both endoderm development and fetal hematopoietic stem cell (HSC) maintenance. While endoderm-derived organs are well known to originate from Sox17-expressing cells, it is less certain whether fetal HSCs also originate from Sox17-exp ...

Wiley-Blackwell2012

Patterning and shaping the endoderm in vivo and in culture

Marine Marie Kraus, Anne Grapin-Botton

The definitive endoderm (DE) was first defined as the innermost germ layer found in all metazoan embryos. During development, it gives rise to a vast array of specialized epithelial cell types lining the respiratory and digestive systems, and contributes t ...

Elsevier2012

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Ectoderm

Reaction wavefront theory of notochord segment patterning

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance

In vitro modeling of early mouse development

What are you synching about? Emerging complexity of Notch signaling in the segmentation clock

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Performance study of a UWB antenna in proximity to a human arm

Dual Lineage-Specific Expression of Sox17 During Mouse Embryogenesis

Patterning and shaping the endoderm in vivo and in culture

Graph Chatbot

Chat with Graph Search

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance

In vitro modeling of early mouse development

What are you synching about? Emerging complexity of Notch signaling in the segmentation clock

Dual Lineage-Specific Expression of Sox17 During Mouse Embryogenesis

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Patterning and shaping the endoderm in vivo and in culture

Performance study of a UWB antenna in proximity to a human arm

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation