Concept

Transverse myelitis

Related publications (11)

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Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...

OXFORD UNIV PRESS2023

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Reto Meuli, Cristina Granziera, Jonas Richiardi, João Pedro Forjaco Jorge, Mario Joao Fartaria de Oliveira, Francesco La Rosa

The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine is limited by inter-rater variability and the expenditure of time associated with manual assessment. We describe a ...

2020

Soft multimodal neural interfaces for unravelling sensory neurological circuits

Frédéric Pierre Gérald Michoud

Diseases or injuries affecting the nervous system can dramatically disrupt the quality of life. Despite extensive efforts towards treating dysfunctional nervous systems, the pharmacological and electrical approaches generally involved lack the temporal and ...

EPFL2019

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An enzymatically cross-linked polyethylene glycol (PEG)-based hydrogel was engineered to promote and align nerve cells in a three-dimensional manner. To render the injectable, otherwise bioinert, PEG-based material supportive for cell growth, its mechanica ...

AMER CHEMICAL SOC2019

Required growth facilitators propel axon regeneration across complete spinal cord injury

Grégoire Courtine, Mark Andrew Anderson, Nicholas David James, Cheng Wang, Sabry Leonardo Barlatey, Michael V. Sofroniew, Zhigang He

Transected axons fail to regrow across anatomically complete spinal cord injuries (SCI) in adults. Diverse molecules can partially facilitate or attenuate axon growth during development or after injury1,2,3, but efficient reversal of this regrowth failure ...

2018

Due to a distortion of its hexagonal unit cell along the c-axis compared to hexagonal-close-packed metals (c/a = 1.856 instead of 1.633), zinc is characterised by a large anisotropy of its solid-liquid interfacial energy. While previous studies have focuse ...

EPFL2015

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

Grégoire Courtine, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler

Experimental and clinical studies suggest that primate species exhibit greater recovery after lateralized compared to symmetrical spinal cord injuries. Although this observation has major implications for designing clinical trials and translational therapi ...

American Association for the Advancement of Science2015

Conventional magnetic resonance imaging (MRI) techniques are highly sensitive to detect multiple sclerosis (MS) plaques, enabling a quantitative assessment of inﬂammatory activity and lesion load. In quantitative analysis of focal lesions, manual or semi-a ...

2011

This paper addresses the problem of correct recovery of multiple sparse correlated signals using distributed thresholding. We consider the scenario where multiple sensors capture the same event, but observe different signals that are correlated by local tr ...

2009

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Severe lesions of the rodent or human spinal cord lead to permanent paralysis of the legs. Here, we review novel evidences suggesting that interventions combining pharmacological and electrical stimulations of the spinal cord have a high potential to promo ...

2009

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