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In five-dimensional Euclidean geometry, the cyclotruncated 5-simplex honeycomb or cyclotruncated hexateric honeycomb is a space-filling tessellation (or honeycomb). It is composed of 5-simplex, truncated 5-simplex, and bitruncated 5-simplex facets in a ratio of 1:1:1. Its vertex figure is an elongated 5-cell antiprism, two parallel 5-cells in dual configurations, connected by 10 tetrahedral pyramids (elongated 5-cells) from the cell of one side to a point on the other. The vertex figure has 8 vertices and 12 5-cells. It can be constructed as six sets of parallel hyperplanes that divide space. The hyperplane intersections generate cyclotruncated 5-cell honeycomb divisions on each hyperplane.