Concept

Female infertility

Related publications (20)

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

Didier Trono, Jeffrey Alan Hubbell, Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, Seung Tae Lee, Miriella Carmela Pasquier, Jong Eun Ihm, Vivianne Greenwood

Lymphatic vessels surround follicles within the ovary, but their roles in folliculogenesis and pregnancy, as well as the necessity of Lymphangiogenesis in follicle maturation and health, are undefined. We used systemic delivery of mF4-31C1, a specific anta ...

Elsevier Science Inc2013

Distinguishing Sitting and Standing Activities Using a Wearable Barometric Pressure Monitor

Kamiar Aminian, Anisoara Ionescu, Julien Chardonnens, Fabien Massé, Alan Kevin Bourke

Recent advancements in wearable inertial sensor technology have enabled extensive research into activity classification. However, the distinction between the sitting and standing activities using trunk-worn wearable monitoring systems remains challenging, ...

2013

Long-term programming of enhanced aggression by peripuberty stress in female rats

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

Human literature has linked adverse early life experiences with an increased risk to develop violent behaviors in both boys and girls. We have previously shown that male rats submitted to stress during the peripuberty period display as adults abnormal aggr ...

Elsevier2013

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Alexandre Gattiker

Mammalian spermatogenesis is a process that involves a complex expression program in both somatic and germ cells present in the male gonad. A number of studies have attempted to define the transcriptome of male meiosis and gametogenesis in rodents and prim ...

Oxford University Press2012

Proangiogenic Tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease

Michele De Palma, Daniela Biziato, Stefano Ferrari

Endometriosis affects women of reproductive age, causing infertility and pain. Although immune cells are recruited in endometriotic lesions, their role is unclear. Tie2-expressing macrophages (TEMs) have nonredundant functions in promoting angiogenesis and ...

2011

Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats

Dominique Pioletti, Randoald Müller, Bastian Peter

Patients with osteoporosis and joint disabilities represent a constant growing and challenging population to be treated in the musculoskeletal clinical field. Especially in the case of total hip arthroplasty, new solutions should be developed to compensate ...

2006

C. elegans tubby regulates life span and fat storage by two independent mechanisms

Bart Deplancke

In C. elegans, similar to in mammals, mutations in the tubby homolog, tub-1, promote increased fat deposition. Here, we show that mutation in tub-1 also leads to life span extension dependent on daf-16/FOXO. Interestingly, function of tub-1 in fat storage ...

2005

Prolactin controls mammary gland development via direct and indirect mechanisms

Cathrin Brisken

The inactivation of the prolactin receptor gene by homologous recombination has made it possible to investigate the role of prolactin signaling in mammary gland development without resort to ablative surgery of the endocrine glands. In knockout mice lackin ...

1999

Modulators of ob gene and screening methods therefor

Johan Auwerx

This invention relates to the isolation and cloning of the promoter and other control regions of a human ob gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the ...

1996

High susceptibility for diploidy in ovulated oocytes from XO mice

Friedrich Beermann

Adult female mice of the "sensitive" NMRI/Han strain ovulate diploid oocytes after gonadotropin treatment. Other mouse strains are "non-sensitive" with respect to the ovulation of such diploid oocytes. In this study we combined the impaired ovarian situati ...

1986

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