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Purpose: This study was designed and conducted to validate the reference values of hematological parameters for healthy adult male and female residents of Kabul city, Afghanistan. Methodology: In this cross-sectional study, the samples were collected accor ...
Background: The gut microbiome and iron status are known to play a role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD), although their complex interaction remains unclear. Results: Here, we applied an integrative systems medicine approa ...
The mechanical action on iron of the first horseshoe electro-magnets (1824) was obvious. Their use to investigate more subtle magnetic, magneto-optical, atomic or nuclear properties of matter began in 1845 with Faraday. Until the first iron-less Bitter mag ...
Here we report the effect of UO2+⋯Fe2+ cation–cation interactions on the redox properties of uranyl(V) complexes and on their stability with respect to proton induced disproportionation. The tripodal heptadentate Schiff base trensal3− ligand allowed the sy ...
Mass spectrometry (MS) is an essential detection tool in bioanalytical chemistry owing to its exceptional selectivity and sensitivity, paired with rapid analyte identification and quantification. In this thesis, two classical MS and a newly developed ioniz ...
Tryptophan is commonly used to study protein structure and dynamics, such as protein folding, as a donor in fluorescence resonant energy transfer (FRET) studies. By using ultra-broadband ultrafast two-dimensional (2D) spectroscopy in the ultraviolet (UV) a ...
American Association for the Advancement of Science2013
To maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought to be controlled by hepcidin, a polypeptide secreted by hepatocytes in response to high serum iron. Hepcidin limits basolateral iron efflux from the duodenal epit ...
This work describes different strategies for the detection of biologically relevant analytes. The main goal was to achieve sensing in water, which is a prerequisite for application to real biological samples. In several cases, we could demonstrate that our ...
Ferritin plays a central role in iron metabolism by acting both as iron storage and detoxifying protein. We have generated a ferritin H allele with loxP sites and studied the conditional ferritin H deletion in adult mice. Ten days after Mx-Cre induced dele ...
Droplet‐based microfluidics allows the generation and manipulation of many independent microreactors (pico‐ to nanoliter volumes) optionally hosting human cells. However, one limitation is that mammalian cells within droplets are not fully accessible from ...
