Publications related to Diagnosis of HIV/AIDS

HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A

Jacques Fellay

A recent genome-wide association study (GWAS) involving patients with hemophilia A who were exposed to but uninfected with human immunodeficiency virus type 1 (HIV-1) did not reveal genetic variants associated with resistance to HIV-1 infection, beyond hom ...

Oxford University Press2014

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Jacques Fellay, Christian Axel Wandall Thorball, Amalio Telenti, Istvan Bartha, Julia di Iulio

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to pr ...

Public Library Science2014

A Quantitative Approach to Evaluate the Impact of Fluorescent Labeling on Membrane-Bound HIV-Gag Assembly by Titration of Unlabeled Proteins

Suliana Manley, Romain Wyss

The assembly process of the human immunodeficiency virus 1 (HIV-1) is driven by the viral polyprotein Gag. Fluorescence imaging of Gag protein fusions is widely performed and has revealed important information on viral assembly. Gag fusion proteins are com ...

Public Library Science2014

Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons

Jacques Fellay, Amalio Telenti, Xuan Li

Background. Persons infected with human immunodeficiency virus (HIV) have increased rates of coronary artery disease (CAD). The relative contribution of genetic background, HIV-related factors, antiretroviral medications, and traditional risk factors to CA ...

Oxford University Press2013

Influence of HLA-C Expression Level on HIV Control

Jacques Fellay

A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression ...

American Association for the Advancement of Science2013

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

Jacques Fellay, Amalio Telenti

Human genetic variation contributes to differences in susceptibility to HIV-1 infection. To search for novel host resistance factors, we performed a genome-wide association study (GWAS) in hemophilia patients highly exposed to potentially contaminated fact ...

Oxford University Press2013

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

Jacques Fellay, Amalio Telenti, Istvan Bartha

HIV-1 sequence diversity is affected by selection pressures arising from host genomic factors. Using paired human and viral data from 1071 individuals, we ran >3000 genome-wide scans, testing for associations between host DNA polymorphisms, HIV-1 sequence ...

Elife Sciences Publications Ltd2013

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

Jacques Fellay, Amalio Telenti, Natalie Muller, Patrick Taffe

The antiviral potency of the cytokine IFN-α has been long appreciated but remains poorly understood. A number of studies have suggested that induction of the apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 (APOBEC3) and bone marrow stromal ce ...

National Academy of Sciences2012

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Diagnosis of HIV/AIDS

HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Genetic analysis of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis

A Quantitative Approach to Evaluate the Impact of Fluorescent Labeling on Membrane-Bound HIV-Gag Assembly by Titration of Unlabeled Proteins

Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons

Influence of HLA-C Expression Level on HIV Control

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

HLA-Bw4 identifies a population of HIV-infected patients with an increased capacity to control viral replication after structured treatment interruption

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

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HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

A Quantitative Approach to Evaluate the Impact of Fluorescent Labeling on Membrane-Bound HIV-Gag Assembly by Titration of Unlabeled Proteins

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Genetic analysis of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis

HLA-Bw4 identifies a population of HIV-infected patients with an increased capacity to control viral replication after structured treatment interruption

Influence of HLA-C Expression Level on HIV Control

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons