Chromosome 17
Chromosome 17 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 17 spans more than 84 million base pairs (the building material of DNA) and represents between 2.5 and 3% of the total DNA in cells. Chromosome 17 contains the Homeobox B gene cluster. The following are some of the gene count estimates of human chromosome 17. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Genes on human chromosome 17 The following is a partial list of genes on human chromosome 17. For complete list, see the link in the infobox on the right. The following are some of the genes and their corresponding Cytogenetic location on chromosome 17: The following diseases are related to genes on chromosome 17: 17q12 microdeletion syndrome Koolen–de Vries syndrome Alexander disease Andersen–Tawil syndrome Aneurysmal bone cyst Birt–Hogg–Dubé syndrome Bladder cancer Breast cancer Bruck syndrome Campomelic dysplasia Canavan disease Cerebroretinal microangiopathy with calcifications and cysts Charcot–Marie–Tooth disease Chronic lymphocytic leukaemia, tp53 Corticobasal degeneration Cystinosis Depression Ehlers–Danlos syndrome Epidermodysplasia verruciformis Frontotemporal dementia and parkinsonism linked to chromosome 17 Galactosemia Glycogen storage disease type II (Pompe disease) Hereditary neuropathy with liability to pressure palsies Howel–Evans syndrome Li–Fraumeni syndrome Maturity onset diabetes of the young type 5 Miller–Dieker syndrome Multiple synostoses syndrome Neurofibromatosis type I Nonsyndromic deafness Obsessive–compulsive disorder Osteogenesis imperfecta Potocki–Lupski syndrome Proximal symphalangism Sanfilippo sy
