Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.
Triclosan was developed in 1966. A 2006 study recommended showering with 2% triclosan as a regimen in surgical units to rid patients' skin of methicillin-resistant Staphylococcus aureus (MRSA). While finding benefit for consumers and no proven risk to human health, but assumed risk of antibiotic resistance, in December 2017, the FDA announced that "consumer antiseptic washes" containing triclosan or 23 other ingredients marketed as antimicrobials were prohibited without pre-market approval. The FDA did find that triclosan in Colgate Total toothpaste helped prevent gingivitis.
Triclosan was used as a hospital scrub in the 1970s. Prior to being banned, it had expanded commercially and was a common ingredient in soaps (0.10–1.00%), shampoos, deodorants, toothpastes, mouthwashes, cleaning supplies, and pesticides. It also was part of consumer products, including kitchen utensils, toys, bedding, socks, and trash bags.
As of 2017, there were five registrations for triclosan with the EPA. The antimicrobial active ingredient is added to a variety of products where it acts to slow or stop the growth of bacteria, fungi, and mildew. In commercial, institutional, and industrial equipment uses, triclosan is incorporated in conveyor belts, fire hoses, dye bath vats, or ice-making equipment as an antimicrobial. Triclosan may be directly applied to commercial HVAC coils, where it prevents microbial growth that contributes to product degradation.