Concept

Spontaneous recovery

Related publications (27)

A VTA to Basal Amygdala Dopamine Projection Contributes to Signal Salient Somatosensory Events during Fear Learning

Ralf Schneggenburger, Olexiy Kochubey, Wei Tang, Michael Kintscher

The amygdala is a brain area critical for the formation of fear memories. However, the nature of the teaching signal(s) that drive plasticity in the amygdala are still under debate. Here, we use optogenetic methods to investigate the contribution of ventra ...

2020

Subjective feeling of re‐experiencing past events using immersive virtual reality prevents a loss of episodic memory

Olaf Blanke, Bruno Herbelin, Andrea Serino, Robin Mange, Lucie Bréchet

Introduction: Personally meaningful past episodes, defined as episodic memories (EM), are subjectively re-experienced from the natural perspective and location of one's own body, as described by bodily self-consciousness (BSC). Neurobiological mechanisms o ...

2020

One-shot learning and behavioral eligibility traces in sequential decision making

Michael Herzog, Wulfram Gerstner, Kerstin Preuschoff, Marco Philipp Lehmann, He Xu, Vasiliki Liakoni

In many daily tasks, we make multiple decisions before reaching a goal. In order to learn such sequences of decisions, a mechanism to link earlier actions to later reward is necessary. Reinforcement learning (RL) theory suggests two classes of algorithms s ...

2019

Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Laurijn Rianne Draaisma

Stroke is a main cause for long-term disability. Stroke symptoms cover various domains, e.g., motor, sensory, language, or other cognitive functions. In clinical practice and rehabilitation research, especially motor impairment attracts much attention. How ...

2018

The dopaminergic VTA - basal amygdala projection contributes to signal aversive state in fear memory

Wei Tang

Dopamine released from midbrain neurons is an important neuromodulatory signal during associative learning in many forebrain circuits. One model of associative learning is auditory cued fear learning, during which an innocuous sensory percept like a tone ( ...

EPFL2018

Involvement of CRFR1 in the basolateral amygdala in the immediate fear extinction deficit

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Fiona Hollis

Several animal and clinical studies have highlighted the ineffectiveness of fear extinction sessions delivered shortly after trauma exposure. This phenomenon, termed the immediate extinction deficit, refers to situations in which extinction programs applie ...

2016

Isoform switching of steroid receptor co-activator-1 attenuates glucocorticoid-induced anxiogenic amygdala CRH expression

Maladaptive glucocorticoid effects contribute to stress-related psychopathology. The glucocorticoid receptor (GR) that mediates many of these effects uses multiple signaling pathways. We have tested the hypothesis that manipulation of downstream factors (' ...

Nature Publishing Group2016

MOOC Learning in Spontaneous Study Groups: Does Synchronously Watching Videos Make a Difference?

Pierre Dillenbourg, Guillaume Zufferey, Nan Li, Himanshu Verma, Afroditi Skevi

Study groups are common approaches for students to study together at schools. However, little is known about how this approach is suited to MOOC based learning, where learners watch and discuss MOOC lecture videos in a collaborative manner. Watching MOOCs ...

P.A.U. Education2014

On the resilience of remote traumatic memories against exposure therapy-mediated attenuation

Johannes Gräff

How to attenuate traumatic memories has long been the focus of intensive research efforts, as traumatic memories are extremely persistent and heavily impinge on the quality of life. Despite the fact that traumatic memories are often not readily amenable to ...

2014

Expanding Eye-Tracking Methods to Explain the Socio-Cognitive Effects of Shared Annotations

Andrea Mazzei

Social technologies are leading to transformations in education, by empowering the way learners connect to each other, by introducing new means for teaching and learning and by reshaping the way knowledge is delivered. Annotating texts is a learning strate ...

EPFL2013

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