Concept

Product activation

Related publications (5)

Whole-genome doubling drives oncogenic loss of chromatin segregation

Elisa Oricchio, Daniele Tavernari, Natalya Katanayeva, Ruxandra-Andreea Lambuta, Juan Diaz Miyar, Giovanni Ciriello

Whole-genome doubling (WGD) is a recurrent event in human cancers and it promotes chromosomal instability and acquisition of aneuploidies(1-8). However, the three-dimensional organization of chromatin in WGD cells and its contribution to oncogenic phenotyp ...

NATURE PORTFOLIO2023

Structural to functional synaptic conversion

Henry Markram, Felix Schürmann, Sean Lewis Hill, Eilif Benjamin Muller, Michael Reimann, James Gonzalo King

Computer-implemented methods, software, and systems for determining functional synapses from given structural touches between cells in a neuronal circuit are described. One computer-implemented method for determining functional synapses from predetermined ...

Technology Transfer Office EPFL2015

Analysis of radioactivity releases in the MEGAPIE reference accident

Konstantin Mikityuk

A computer model for the MEGAwatt Pilot Target Experiment (MEGAPIE) was developed, verified and applied to the analysis of the reference accident, resulting from the hypothetical loss of a Pb–Bi inventory and subsequent cooling down of the target with free ...

2008

Catalytic hydrogenation by triruthenium clusters: A mechanistic study with parahydrogen-induced polarization

Paul Joseph Dyson

The reactivity of the cluster family [Ru-3(CO)(12-x)(L)x] (in which L = PMe3, PMe2Ph, PPh3 and PCy3, x = 1 - 3) towards hydrogen is described. When x=2, three isomers of [Ru-3(H)(mu-H)(CO)(9)(L)(2)] are formed, which differ in the arrangement of their equa ...

2003

A Systems Perspective on the Quality Description of Software Components

Alain Wegmann, Otto Preiss

In this paper we present our motivations for proposing of a generic model for the description of quality attributes of software artifacts, in particular suited to software components. The conceptual ideas for our quality description model are derived from ...

2002

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