eLife is a not-for-profit, peer-reviewed, open access, scientific journal for the biomedical and life sciences. It was established at the end of 2012 by the Howard Hughes Medical Institute, Max Planck Society, and Wellcome Trust, following a workshop held in 2010 at the Janelia Farm Research Campus. Together, these organizations provided the initial funding to support the business and publishing operations. In 2016, the organizations committed US3,000 for papers accepted for publication. This charge was reduced to US$2,000 in 2022 after the adoption of a new model without accept/reject decisions. Authors with insufficient funding are eligible for a fee waiver. The journal is abstracted and indexed in Medline, BIOSIS Previews, Chemical Abstracts Service, Science Citation Index Expanded, and Scopus. According to the Journal Citation Reports, the journal has a 2018 impact factor of 7.080. The journal opposes the over-reliance on the impact factor by the scientific community. In an interview, Howard Hughes Medical Institute then President Robert Tjian reflected on eLife and noted, "The other big thing is, we want to kill the journal impact factor. We tried to prevent people who do the impact factors from giving us one. They gave us one anyway a year earlier than they should have. Don't ask me what it is because I truly don't want to know and don't care." The eLife Podcast is produced by BBC Radio presenter and University of Cambridge consultant virologist Chris Smith of The Naked Scientists.