Concept
Nucleophilic abstraction
Related publications (5)
Organocatalytic Nucleophilic Addition of Hydrazones to Imines: Synthesis of Enantioenriched Vicinal Diamines
Qian Wang, Jieping Zhu, Yang Wang
In the presence of a catalytic amount of chiral phosphoric acid, nucleophilic addition of N-monosubstituted hydrazones to N-Boc imines affords differentially protected vicinal diamines in the form of b-amino N,N’-dialkyldiazenes in excellent yields with hi ...
Wiley-Blackwell2017α-Oxo-Ketenimines from Isocyanides and α-Haloketones: Synthesis and Divergent Reactivity
Qian Wang, Jieping Zhu, Mathias Mamboury
The palladium-catalyzed reaction of a-haloketones with isocyanides afforded -oxo-ketenimines through alpha-hydride elimination of the beta-oxo-imidoyl palladium intermediates. Reaction of these relatively stable alpha-oxo ketenimines with nucleophiles suc ...
Wiley-Blackwell2017Mild synthesis of mercaptonitriles from vinyl nitriles and their cyclization reactions
Thiol-ene addition of thioacetic acid A is widely used in the synthesis of thiols from vinyl precursors, but so far has not been conducted on non-conjugated vinyl nitriles. The challenge when vinyl nitriles are used is to selectively conduct the thiol-ene ...
Royal Soc Chemistry2016Radiolyse des n-alcanes en phase liquide
Contributions of radical and non-radical processes have been determined in the formation of radiolysis products of n-heptane, n-octane, n-nonane and n-decane in a large range of temperature. Calculations are based on the combination and the dismutation of ...
s.n.1974Preparation of fluorocyclopropanes by reductive dechlorination of chlorofluorocyclopropanes
Treatment of Cl2CF2 with a base in the presence of an olefin gave chlorofluorocyclopropanes (I), which were distd. in a spinning band column and taken up in tetrahydrofuran (THF). This soln. was added dropwise to a stoichiometric amt. of Na in liquid NH3 a ...
1967