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The need for interfacing structural biology and biophysics to molecular evolution is being increasingly recognized. One part of the big problem is to understand how physics and chemistry shape the sequence space available to functional proteins, while sati ...
The LHCb experiment is designed to perform high-precision measurements of CP-violation and rare decays of B hadrons at the Large Hadron Collider. The Silicon Tracker (ST) is a silicon strip detector intended to precisely measure the particle trajectories p ...
We address the mining of sequential activity patterns from document logs given as word-time occurrences. We achieve this using topics that models both the cooccurrence and the temporal order in which words occur within a temporal window. Discovering such t ...
We present a comparative study of residue usage correlations of various organism protein sets of diverse phylogenetic species and of open reading frames of several large human viral genomes. Our correlation analysis reveals three major tendencies: (i) char ...
The sequence profile method (Gribskov M, McLachlan AD, Eisenberg D, 1987, Proc Natl Acad Sci USA 84:4355-4358) is a powerful tool to detect distant relationships between amino acid sequences. A profile is a table of position-specific scores and gap penalti ...
We address the mining of sequential activity patterns from document logs given as word-time occurrences. We achieve this using topics that models both the cooccurrence and the temporal order in which words occur within a temporal window. Discovering such t ...