Concept

Artery

Related publications (94)

A constitutive formulation of arterial mechanics including vascular smooth muscle tone

Nikolaos Stergiopoulos, Martin Zulliger, Alexander Rachev

A pseudo-strain energy function (pseudo-SEF) describing the biomechanical properties of large conduit arteries under the influence of vascular smooth muscle (VSM) tone is proposed. In contrast to previous models that include the effects of smooth muscle co ...

2004

A strain energy function for arteries accounting for wall composition and structure

Nikolaos Stergiopoulos, Martin Zulliger

Identification of a Strain Energy Function (SEF) is used when describing the complex mechanical properties of soft biological tissues such as the arterial wall. Classic SEFs, such as the one proposed by Chuong and Fung (J. Biomech. Eng. 105(3) (1983) 268), ...

2004

One dimensional and multiscale models for blood flow circulation

The aim of this work is to provide mathematically sound and computationally effective tools for the numerical simulation of the interaction between fluid and structures as occurring, for instance, in the simulation of the human cardiovascular system. This ...

EPFL2004

Multidimensional pharmacokinetic models applied to the design of drug-eluting stents

Paolo Zunino

Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The medical drug is, in general, aimed at healing the vascular tissues injured after implantation and to prevent restenosis. In spite of their apparent simplic ...

2004

Peptide/protein hybrid materials: Enhanced control of structure and improved performance through conjugation of biological and synthetic polymers

Harm-Anton Klok

The conjugation of peptides/proteins and synthetic polymers is a useful strategy to overcome some of the limitations related to the use of the individual components. This review will highlight two aspects: enhanced structural control at the nanometer level ...

2004

Implant with deflector for intravascular dilation

Nikolaos Stergiopoulos

An intravascular dilator includes a central body acting as deflector o the blood flow to increase the value of shear stress to the artery wall. Flexible spires soldered to the deflector are radially extensible from a first diameter substantially equal to t ...

2003

Recruitment of smooth muscle cells and arterial vasomotion

Jean-Jacques Meister, Jean-Louis Bény, Alexander Schuster, Mathieu Lamboley

Investigating the recruitment and synchronization of smooth muscle cells (SMCs) is the key to understanding the physical mechanisms leading to contraction and spontaneous diameter oscillations of arteries, called vasomotion. We improved a method that allow ...

2003

Automated Parameterization and Patching of Bifurcating Vessels

Recent developments in computational modeling of human arteries have opened the possibility of performing subject-specific analyses on increasingly larger numbers of subjects. This achievement will eventually lead to a better understanding of the role of g ...

2003

PPAR agonists in the treatment of atherosclerosis

Johan Auwerx

Current treatment for atherosclerotic heart disease consists mainly of the administration of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors or 'statin' class of drugs. Statins, which lower low-density lipoprotein cholesterol levels an ...

2003

A one-dimensional model for blood flow: Application to vascular prosthesis

Alfio Quarteroni, Fabio Nobile, Luca Formaggia

We investigate a one-dimensional model of blood flow in human arteries. In particular, we consider the case when an abrupt variation of mechanical characteristic of artery is caused by the presence of a vascular prosthesis. The derivations of the model and ...

Springer2002

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