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Ca2+-evoked transmitter release shows a high dynamic range over spontaneous release. We investigated the role of the Ca2+ sensor protein, Synaptotagmin2 (Syt2), in both spontaneous and Ca2+-evoked release under direct control of presynaptic Ca2+, usin ...
Neocortical layer 5 (L5) pyramidal cells have at least two spike initiation zones: Na+ spikes are generated near the soma, and Ca2+ spikes at the apical dendritic tuft. These spikes interact with each other and serve as signals for synaptic plasticity. The ...
This paper reports on silicon-based microprobes, 8 mm long and 250 mu m x 250 mu m cross-section, comprising four recessed biosensor microelectrodes (50 mu m x 150 mu m) per probe shank coated with an enzymatic layer for the selective detection of choline ...
Combined all-electrical spin-wave and micro-focused Brillouin light scattering spectroscopies have been used to study spin-wave eigenmodes in bicomponent lattices formed by periodic Co nanodisks introduced in nanotroughs etched into a thin Ni80Fe20 film. W ...
We derive a plausible learning rule updating the synaptic efficacies for feedforward, feedback and lateral connections between observed and latent neurons. Operating in the context of a generative model for distributions of spike sequences, the learning me ...
Neocortical layer 5 (L5) pyramidal cells have at least two spike initiation zones: Na(+) spikes are generated near the soma, and Ca(2+) spikes at the apical dendritic tuft. These spikes interact with each other and serve as signals for synaptic plasticity. ...
At the end of the 1980’s, a series of existing bridges in Switzerland were equipped with a network of hydrostatic leveling devices, with the aim of following their longterm behavior. Some of the bridges were known to exhibit a steady increase in their defo ...
While existing studies on YouTube’s massive user-generated video content have mostly focused on the analysis of videos, their characteristics, and network properties, little attention has been paid to the analysis of users’ long-term behavior as it relates ...
Gene transcription is essential for the establishment and the maintenance of long-term memory (LTM) and for long-lasting forms of synaptic plasticity. The molecular mechanisms that control gene transcription in neuronal cells are complex and recruit multip ...
Stress can affect the establishment and maintenance of social hierarchies. In the present study, we investigated the role of increasing corticosterone levels before or just after a first social encounter between two rats of a dyad in the establishment and ...